CRF Senior Clinical Research Nurse

NHS; London; On-site; GBP 40,000 - 60,000; Full time

Job summary

An established industry player is seeking a senior research nurse to join their clinical research facility. This role involves providing clinical leadership, managing a diverse team, and ensuring high-quality research delivery. The ideal candidate will have extensive experience in clinical trials, strong communication skills, and the ability to mentor junior staff. You will play a crucial role in coordinating early-phase studies and advocating for patient well-being. If you are passionate about advancing clinical research and thrive in a collaborative environment, this opportunity is perfect for you.

Qualifications

• Registered adult nurse with ongoing professional development.
• Experience in NHS clinical research and mentoring.

Responsibilities

• Lead participant communication and support for trial participants.
• Manage research portfolio and coordinate clinical trials.

Skills

Excellent communication

Multitasking

Leadership and team management

Attention to detail

Clinical trials experience

Education

Degree-level professional knowledge

ICH GCP certification

Tools

Basic laboratory skills

SACT accreditation

Job description

Guy's and St Thomas' NHS Foundation Trust

We are seeking an exceptional senior research nurse to join the clinical research facility (CRF) research team. This role provides clinical leadership for our expanding research portfolio, manages junior research staff, and supports the team in delivering high-quality research.

You will manage your team's research portfolio, review protocols and amendments, and identify resource implications. Responsibilities include line management, staff recruitment, training, support, and mentoring.

Applicants must be registered adult nurses with ongoing professional development. Experience in NHS clinical research, a strong clinical background, and a willingness to develop others are essential. Key skills include excellent communication, multitasking, meeting deadlines, and managing a patient caseload across various studies.

The post requires shift work, including days, evenings, nights, and weekends, to ensure patient safety and trial delivery.

Main duties of the job

The role involves coordinating early-phase translational clinical research, collaborating with personnel across the two CRFs to support patients and volunteers, supervising the administration of experimental therapies, monitoring drug effects, and possibly gaining ethical approval, data collection, interviews, and data entry.

You will advocate for patients, providing advice and information to support informed decision-making regarding trial participation.

Your responsibilities include contributing to operational improvement projects, attending feasibility and initiation meetings, managing supplies and equipment, supporting external staff orientation, and performing clinical tasks such as phlebotomy, blood analysis, drug administration, and clinical observation.

The role requires working autonomously, with delegated clinical decision-making, closely collaborating with investigators and multidisciplinary teams.

About us

You will interact with a broad range of stakeholders involved in trial delivery, including clinicians, research and healthcare managers, staff, participants, and external bodies like hospitals, NHS trusts, pharmaceutical companies, and sponsors. You will lead a dedicated research nursing team.

Job responsibilities

The post holder will:

• Lead participant communication and well-being, providing specialist advice on research nursing.
• Support screening, information provision, clinical follow-up, data collection, and safety reporting for research participants.
• Establish and maintain strategic relationships with clinicians, researchers, and health managers for trial implementation.
• Collaborate with trial coordinators, data managers, and developers to ensure compliance with GCP, data protection, and research governance.
• Develop training materials for research staff, including study-specific and GCP training.
• Monitor participant well-being and address issues proactively.
• Serve as a central contact for trial-specific procedures, including participant support, eligibility assessment, consent, and sample management.

Person Specification

Knowledge/Qualifications

• Degree-level professional knowledge, supplemented by specialist training or courses.
• ICH GCP certification.

Skills

• Extensive experience in clinical trials, teaching, and mentoring.
• Knowledge of UK clinical trial regulations, GCP, and Helsinki Declaration.
• Ability to deliver specialized care and advice for trial participants.
• Attention to detail in data collection.
• Experience managing complex relationships.
• Leadership and team management skills.
• Experience mentoring staff and delivering early-phase studies.

Experience

• Excellent communication skills for handling sensitive information and engaging with patients.
• Ability to plan and organize complex activities.
• Support and develop a specialized nursing service.
• Dexterity for venepuncture, injections, and sample handling.
• Basic laboratory skills.
• Ability to train junior staff on protocols and GCP.
• Strong interpersonal skills and ability to work independently or as part of a team.
• Leadership capability for guiding research teams.
• SACT accreditation.

Disclosure and Barring Service Check

This role is subject to DBS checks due to the Rehabilitation of Offenders Act.

Address

Cross-site - Guy's CRF and St Thomas' CRF