CRA II

KCR Placement; Reading; On-site; GBP 42,000 - 64,000; Full time

Benefits offered by this job

Annual leave

Health insurance

Pension plan

Employee assistance programme

Job summary

ICON plc is seeking an experienced CRA II or Senior CRA to join our Early Phase team in the UK. You will monitor a small portfolio of 3–4 sites across the country, maintaining high quality oversight, patient safety and data integrity in early development studies.

Working with investigators and sponsors, you’ll manage qualification, initiation, monitoring and close-out activities while mentoring less experienced colleagues and ensuring regulatory compliance across trials.

Qualifications

• ICH-GCP knowledge and regulatory understanding.
• Strong relationship-building and communication skills.
• Ability to travel across the UK and work independently in a global study team.

Responsibilities

• Manage site qualification, initiation, monitoring and close-out across UK Early Phase studies.
• Build partnerships with investigators and site teams to ensure study success.
• Ensure patient safety, protocol compliance and data integrity throughout the trial lifecycle.
• Review study data, resolve site queries and mitigate risks proactively.
• Support sponsors and project teams with early development programme challenges.
• Provide guidance to sites and internal stakeholders as a clinical research expert.

Skills

Independent monitoring

Communication skills

Travel readiness

Education

Life Science degree

Nursing degree

Pharmacy degree

Job description

CRA II/Senior CRA - Early Phase

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a CRA II or Senior CRA within our Early Phase team, you'll play a critical role in studies that sit at the very beginning of the drug development journey, including first-in-human and proof-of-concept research. Working alongside leading investigators, sponsors, and specialist clinical teams, you'll help advance promising new therapies from concept to clinical reality.

Unlike traditional large-scale monitoring roles, you'll focus on a smaller portfolio of approximately 3-4 sites across the UK, enabling you to build strong site relationships, maintain exceptional quality oversight, and make a genuine impact on the success of each study.

What You'll Be Doing

• Managing site qualification, initiation, monitoring and close-out activities across a portfolio of UK Early Phase studies.
• Building strong partnerships with investigators and site teams to ensure study success.
• Ensuring patient safety, protocol compliance, and data integrity throughout the clinical trial lifecycle.
• Reviewing study data, resolving site queries, and proactively identifying and mitigating risks.
• Supporting sponsors and project teams through the unique operational challenges associated with early development programmes.
• Acting as a trusted clinical research expert, providing guidance and support to sites and internal stakeholders.

What We're Looking For

• CRA II: Previous independent monitoring experience across clinical trials.
• Senior CRA: Significant independent monitoring experience with the ability to manage complex studies and act as a mentor for less experienced colleagues.
• Strong understanding of ICH-GCP, regulatory requirements, and clinical trial operations.
• Excellent relationship-building and communication skills.
• Ability to work proactively, independently, and collaboratively within a global study team.
• Life Science, Nursing, Pharmacy, or other relevant healthcare degree (or equivalent experience).
• Able to travel across the UK as required to complete onsite visits

What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here