Clinical Trial Manager

Discover International; Birmingham; On-site; GBP 60,000 - 90,000; Full time

Job summary

Discover International in the UK is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors, coordinating cross-functional teams from start-up through close-out.

You will own end-to-end trial management, oversee site monitoring plans, manage budgets and timelines, and ensure compliance with ICH-GCP and UK/EU regulations. You will line-manage CRAs/CRCs and act as primary contact for sponsors.

Qualifications

• Degree in life sciences or equivalent required.
• Minimum 4+ years in clinical trial management in CRO/pharma/biotech.
• Proven line management or mentoring experience.
• Strong knowledge of ICH-GCP and UK/EU trial regulations.

Responsibilities

• Own end-to-end trial management for assigned studies.
• Line-manage CRAs/CRCs and oversee monitoring plans.
• Serve as primary sponsor contact, provide status updates and risk alerts.
• Develop and manage study budgets, timelines, and vendor oversight.
• Ensure inspection readiness and regulatory compliance.
• Lead site selection, feasibility, and start-up activities.
• Chair internal and sponsor study team meetings.

Skills

Line management

Budget management

Risk-based monitoring

Stakeholder communication

Education

Life sciences degree

Job description

Discover International is partnered with a UK-based CRO is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV clinical trials for pharmaceutical and biotech sponsors, managing cross-functional teams and study timelines from start-up through close-out.

Key Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance
• Serve as primary point of contact for sponsors, providing status updates and risk escalation
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs
• Lead site selection, feasibility assessments, and study start-up activities
• Chair internal and sponsor study team meetings

Skills & Experience

• Life sciences degree (or equivalent experience)
• 4+ years in clinical trial management within a CRO, pharma, or biotech setting
• Proven line management/mentoring experience
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring
• Experience managing study budgets and vendors
• Experience in oncology, rare disease, or cardiovascular trials