Clinical Bioinformatician

NHS; London; On-site; GBP 55,000 - 63,000; Full time

Job summary

Join a leading team as a Clinical Bioinformatician at a prominent NHS facility in London. You will develop and manage bioinformatics pipelines, supporting clinical diagnostics for rare diseases and cancer. This role offers opportunities for professional growth and involvement in innovative projects.

Benefits

Flexible working pattern

Learning opportunities

Funding for advanced qualifications

Qualifications

• Working towards HCPC registration or already registered.
• Experience analyzing next generation sequence data.

Responsibilities

• Maintain and operate bioinformatics pipelines for NGS data.
• Support development and validation of new diagnostic tests.

Skills

Python

Java

Bash

Troubleshooting

Education

BSc in bioinformatics

PhD in bioinformatics

Tools

AWS

DNAnexus

Nextflow

Job description

We are looking for several highly motivated Clinical Bioinformaticians to join our expanding Bioinformatics team at the South East Genomic Laboratory Hub (SEGLH). The posts will be based at either Guy's Hospital or King's College Hospital, but with a planned consolidation to a hub at Blackfriars.

The posts will be part of the team supporting the clinical diagnostics services of both Guy's and King's College Hospitals, covering several rare disease and cancer diagnostic laboratories. You would have the opportunity to develop and troubleshoot both somatic and germline pipelines, develop and manage applications supporting the diagnostic process and manage large datasets for reporting.

The successful applicant will be dedicated and enthusiastic with knowledge and experience of working with NGS pipelines and large datasets, as well as possessing strong programming and troubleshooting experience. Applicants should be good communicators, be able to take initiative, support continual quality improvement and prioritise workload. The role requires consistent attention to detail and excellent organisational skills.

Applicants will be expected to have attained or be working towards HCPC registration. STP trainees in their final year of training, or applicants with relevant MSc or PhD and bioinformatics experience, who are interested in transitioning to a clinical setting, are also encouraged to apply.

Main duties of the job

This is an exciting opportunity to join a dynamic team which is highly valued in Synnovis Genomics. The successful candidate will support existing diagnostic services in the South East and also be involved in a very active programme of assay and technology development.

The role would involve maintaining and operating the bioinformatics pipelines for the processing of next generation sequencing data for both Guys and King's College Hospitals, managing multiple pipelines supporting services for the Genomic Medicine Service.

The post-holders will work with other clinical scientists to support the development, validation and implementation of new/updated diagnostic tests. This will include developing and delivering validated and accredited software for delivery of diagnostic services following clinical best practice guidelines, as well as working with cloud-based infrastructure, local databases and the latest technologies to deliver bioinformatics services.

We support a flexible, hybrid working pattern. The posts will be based at Guy's Hospital or Kings College hospital, though occasional travel to other Synnovis sites, such as other trust sites may be requested.

About us

Your development and learning

You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.

Through our Innovation Accelerator Fund, you can apply for finance to get that new innovative scientific project off the ground, and participate with the wider scientific community through symposiums, conferences and other peer group meetings.

Job responsibilities

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites. However, from 1 April 2024 our people and services will start to move to our Hub laboratory in Blackfriars, Southwark, SE1, with some work remaining in refurbished essential services laboratories across our hospital network, focusing on the rapid turnover of urgent tests. Please do ask your recruiting manager if you wish to find out more.

Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guys & St Thomas NHS Foundation Trust and Kings College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.

The partnership provides services to 1.7 million people living in South East London, as well as to hundreds of thousands of patients from outside the region who use local healthcare services.

The partnership provides diagnostics, testing and digital pathology for hospital trusts, GP services and other healthcare providers.

Guys and St Thomas Hospital Foundation Trust is a major emergency and specialist teaching Trust which has all the specialties associated with a fascinating and career defining case load including: Womens Services, Fetal Medicine, Haematology, Oncology, Transplantation, and is also home to the Evelina Childrens Hospital and the Cancer Centre on the Guys site.

You will be close to the vibrant Borough Market and the South Bank, which are exceptional London locations; perfect places to work and relax next to such iconic venues as Big Ben, The London Eye and The Shard!

Kings College Hospital Foundation Trust is one of the UKs leading NHS Foundation Trusts in specialist teaching. Kings has various divisions including Neurosciences, Haematology, Cancer and Cardiovascular sciences, where there are unlimited opportunities to develop and perfect your career.

Over the last 170 years, Kings has delivered nothing but world class service to all its patients from deprived communities as well as some of the wealthiest in London.

Person Specification

Qualifications

• HCPC Registration (or working towards registration)
• BSc in bioinformatics, biological sciences or related field
• PhD in bioinformatics, biological sciences or related field

Experience

• Experience of analysing next generation sequence data
• Experience of developing, implementing and maintaining bioinformatic data analysis pipelines
• Developing cloud-based genomics apps, e.g. on AWS and DNAnexus
• Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow)

Skills & Knowledge

• Ability to use scripting languages such as Python, Java and Bash
• Ability to trouble shoot and independently solve problems
• Demonstrable broad level understanding of molecular biology and human genetics.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Guy’s Hospital or Kings College Hospital

Depending on experience£55,613 to £62,460 per annum depending on experience

Contract

Permanent

Working pattern

Full-time

Reference number

J206-VIS6731

Job locations

Guy’s Hospital or Kings College Hospital