Cell Line Development Research Associate (Biologics R&D)

Orion Pharma; Cambridge; On-site; GBP 26,000 - 36,000; Full time

Job summary

Orion Pharma is seeking a motivated Research Assistant to join the Cell Line Development (CLD) team at the Biologics R&D Center in Cambridge, UK. The role focuses on generating and characterising stable mammalian cell lines for therapeutic proteins, including antibodies, through routine culture, transfection, clone screening and cell banking.

You will work with Beacon-powered high-throughput screening and collaborate with teams across Cell Line Development, Cell Engineering, Protein Expression

Qualifications

• BSc or MSc in Biotechnology, Cell Biology, Molecular Biology, Biochemistry or a related life-science discipline, or equivalent practical experience.
• Hands-on experience in mammalian cell culture, including aseptic technique and routine cell maintenance.
• Experience with basic molecular biology techniques.
• Ideally, 1–2 years of relevant laboratory experience; biotechnology or pharmaceutical industry experience would be welcome.
• Experience with CHO cells, transfection or stable cell line generation would be an advantage, but not essential.
• Good organisational skills, attention to detail and careful experimental documentation.
• Curiosity, enthusiasm for learning and ability to work collaboratively within a scientific team.

Responsibilities

• Perform routine mammalian cell culture activities, including cell expansion, transfection, passaging and cryopreservation.
• Support the generation, screening and selection of stable CHO cell lines for biologics production.
• Assist with clone expansion and the generation and characterisation of Research Cell Banks (RCBs).
• Support high-throughput clone screening using technologies such as the Beacon platform.
• Prepare samples and coordinate handovers to analytical and process development colleagues.
• Perform basic molecular biology activities to support cell line and construct characterisation, where required.
• Accurately document experimental activities, results and observations, and assist with data analysis and presentation.
• Help maintain laboratory equipment, materials and consumables, following Orion's laboratory, quality and data-integrity procedures.
• Collaborate with colleagues across Cell Line Development, Cell Engineering, Protein Expression and Process Development.

Skills

Mammalian cell culture

Aseptic technique

Molecular biology

Data analysis

Education

BSc in Biotechnology or related

MSc in Biotechnology or related

Tools

Beacon platform

Job description

Orion Pharma is seeking a motivated Research Assistant to join the Cell Line Development (CLD) team at the Biologics R&D Center in Cambridge, UK. The role focuses on generating and characterising stable mammalian cell lines for therapeutic proteins, including antibodies, through routine culture, transfection, clone screening and cell banking.

You will work with Beacon-powered high-throughput screening and collaborate with teams across Cell Line Development, Cell Engineering, Protein Expression