Associate Principal Scientist, QSP

Certara; United Kingdom; On-site; GBP 50,000 - 80,000; Full time

Job summary

A leading company in drug discovery is looking for a motivated Associate Principal Scientist in QSP. The ideal candidate will leverage quantitative systems pharmacology to drive innovative drug development projects. This role offers a dynamic environment, collaborating with global pharmaceutical clients and shaping impactful scientific strategies.

Qualifications

• PhD in life sciences, engineering, or related field required.
• Postdoctoral experience in drug discovery teams preferred.
• Strong publication record essential.

Responsibilities

• Oversee project delivery of quality QSP solutions on time.
• Provide expert technical support for model building.
• Mentor other staff in QSP methodologies.

Skills

Modelling expertise

Technical support

Project delivery

Education

PhD (or equivalent) in life sciences

Postdoctoral experience in systems modelling

Tools

Matlab

Neuron

Job description

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Overview

Certara accelerates medicines using proprietary biosimulation software, technology, and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions, and regulatory agencies across 62 countries.

The Certara Quantitative Systems Pharmacology (QSP) group is a global organization focused on the impactful application of QSP and mechanistic PKPD modeling and simulation in drug discovery and development. We are leading several first-of-its-kind QSP Consortia with more than 10 global pharmaceutical companies and have a rapidly expanding consultancy portfolio. Our QSP scientists work in close collaboration with other Certara staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D. The models are designed in close dialogue with clients and developed with a view to creating user-friendly tools that will inform drug development programs from discovery to regulatory filing. We have unique capability to seamlessly integrate bespoke QSP models into the Simcyp physiologically based pharmacokinetic (PBPK) platform. Besides our well-established leadership in applied QSP approaches in Immunology and Immuno-Oncology, we are now also the leading provider of QSP approaches in neuro-degenerative diseases through Certara’s recent acquisition of the In Silico Biosciences modelling platform.

Overview

Certara accelerates medicines using proprietary biosimulation software, technology, and services to transform traditional drug discovery and development. Its clients include more than 2,000 biopharmaceutical companies, academic institutions, and regulatory agencies across 62 countries.

The Certara Quantitative Systems Pharmacology (QSP) group is a global organization focused on the impactful application of QSP and mechanistic PKPD modeling and simulation in drug discovery and development. We are leading several first-of-its-kind QSP Consortia with more than 10 global pharmaceutical companies and have a rapidly expanding consultancy portfolio. Our QSP scientists work in close collaboration with other Certara staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D. The models are designed in close dialogue with clients and developed with a view to creating user-friendly tools that will inform drug development programs from discovery to regulatory filing. We have unique capability to seamlessly integrate bespoke QSP models into the Simcyp physiologically based pharmacokinetic (PBPK) platform. Besides our well-established leadership in applied QSP approaches in Immunology and Immuno-Oncology, we are now also the leading provider of QSP approaches in neuro-degenerative diseases through Certara’s recent acquisition of the In Silico Biosciences modelling platform.

We are seeking highly motivated and talented QSP modelling experts at all levels, who share our passion for using quantitative approaches to understand and impact complex drug discovery and development questions. Positions are available at various levels of experience across our global locations and for flexible, home-based roles.

Responsibilities

• Overall responsibility for the project delivery of quality QSP solutions on time.
• Provide hands-on technical support for model building when required.
• Work with clients to ensure they receive the expected added value.
• Work with the consortium/ consulting teams to ensure optimal deployment of resources.
• Work with Certara QSP line management to deliver optimum solutions.
• Provide general expert technical input across Certara QSP portfolio.
• Mentor other Certara QSP staff.
  
  

Qualifications

• Postdoctoral experience in systems modelling for drug discovery/ development teams.
• PhD (or equivalent) in life sciences, engineering, computer sciences, mathematics physics or equivalent.
• Good understanding of PKPD, pharmacology and biology and its application in drug discovery and development.
• Very familiar and outstanding hands-on expertise with Matlab, Neuron or other similar modelling software.
• Strong publication record (commensurate with level of experience).

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Business Consulting and Services

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