Associate Director, Clinical Pharmacology – CNS RNAi (UK)

United States Digital Space LLC; Maidenhead; On-site; GBP 120,000 - 150,000; Full time

Job summary

Alnylam Pharmaceuticals is seeking an Associate Director in Clinical Pharmacology. This virtual UK-based role requires leading PK/PD analyses, data interpretation, and strategic input for regulatory submissions. You will collaborate with Research, Regulatory, Project Management, and Bioanalytical teams to drive clinical development of RNAi programs.

The candidate should hold a Ph.D. (or Pharm.D.) in pharmacokinetics/clinical pharmacology with strong communication skills and the ability to work

Qualifications

• Advanced degree with deep experience in pharmaceutical/biotech industry.
• Expertise in clinical pharmacology, PK/PD modeling, and data interpretation.
• Familiarity with international regulatory pharmacology guidelines.

Responsibilities

• Lead analysis, interpretation, integration and reporting of clinical pharmacology data.
• Conduct PK and PK/PD analyses to guide development decisions.
• Provide input for regulatory submissions (IND, NDA, etc.).
• Prepare Protocols, Investigator Brochures and Clinical Study Reports for PK studies.
• Collaborate with Research, Regulatory, and cross-functional teams.
• Prepare abstracts and manuscripts for publications.

Skills

Clinical pharmacology

PK/PD analyses

Data interpretation

Critical thinking

Independent work

Communication skills

English fluency

Education

Ph.D. in Pharmacokinetics / Clinical Pharmacology

Pharm.D. (Pharmacology related)

Tools

Phoenix WinNonlin

R

NONMEM

Job description

Alnylam Pharmaceuticals is seeking an Associate Director in Clinical Pharmacology. This virtual UK-based role requires leading PK/PD analyses, data interpretation, and strategic input for regulatory submissions. You will collaborate with Research, Regulatory, Project Management, and Bioanalytical teams to drive clinical development of RNAi programs.

The candidate should hold a Ph.D. (or Pharm.D.) in pharmacokinetics/clinical pharmacology with strong communication skills and the ability to work