Associate Director Clinical Data Manager

Merck Group; Greater London; On-site; GBP 95,000 - 150,000; Full time

Benefits offered by this job

Medical, dental, vision coverage

Wellness program

PTO and time-off benefits

Job summary

Merck Group is seeking an Associate Director Clinical Data Manager to lead end-to-end data management for global Phase I–IV trials with a focus on oncology, neurology, or immunology. The role requires strategic direction for data collection and quality, plus alignment across global teams in a matrix organization.

You will drive risk-based approaches, explore automation/AI to improve data quality, and oversee CRO/vendor relationships while contributing to SOPs and process improvements.

Qualifications

• Bachelor's or Master’s degree in a scientific or technical discipline — life sciences, data management, or a related field
• 10+ years in clinical data management within pharma/biotech/healthcare with leadership of complex trials
• Deep expertise in end-to-end data management including risk-based data collection, cleaning, eCRF design, external data management, and coding with CDISC standards
• Proven track record managing CRO/vendor relationships, budget monitoring, and in-house sourcing models
• Experience leading global cross-functional teams in a matrix environment and reporting to senior stakeholders
• Strong project management, risk identification/mitigation, and handling multiple priorities independently
• Commitment to continuous improvement and applying external insights to SOPs and data standards
• Experience with Risk Based Data Monitoring; familiarity with automation/AI in data management

Responsibilities

• Lead end-to-end data management delivery for global trials or study portfolios, focusing on complex oncology/neurology/immunology.
• Set strategic direction for data collection, cleaning, review, reconciliation, and quality activities; ensure submission-ready data.
• Serve as primary Clinical Data Management representative at study/program level in a matrix organization.
• Implement risk-based data management strategies and data-flow optimizations for in-house and outsourced studies.
• Oversee CRO/vendor performance, support Health Authority submissions, and mentor colleagues across the function.
• Drive process improvements, SOPs, best practices, and external knowledge sharing to advance data standards.

Skills

Leadership

Clinical Data Management

CDISC/CDASH/SDTM

Risk-based monitoring

Vendor management

Cross-functional leadership

Education

Bachelor's or Master’s in life sciences/related

Job description

Associate Director Clinical Data Manager (all genders)

Work Your Magic with us!
Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role requires to be on-site in our office in Feltham for 3 days per week.

Your role

As a senior team member within Clinical Data Management, you will lead the end-to-end data management delivery for assigned global Phase I–IV clinical trials or a defined study portfolio, with a particular focus on complex oncology, neurology or immunology development. You will set the strategic direction for data collection, cleaning, review, reconciliation, and quality activities, ensuring the accuracy, integrity, completeness, and submission-readiness of clinical trial data. Operating with a high degree of autonomy, you will serve as the primary Clinical Data Management representative at the study/program level, providing operational expertise and aligning cross-functional and global teams in a matrix organization. You will implement risk-based data management and data-flow strategies for in-house and outsourced studies, identify opportunities to apply automation, advanced analytics, and AI-enabled solutions to improve data quality and study execution, oversee CRO/vendor delivery, and support Health Authority submission activities by providing data management expertise and reviewing relevant materials. Beyond your study portfolio, you will actively shape the future of the function through process improvement initiatives, contributing to SOPs and best-practice workstreams, knowledge sharing, and mentoring colleagues to strengthen Clinical Data Management capability across the organization.

Who you are

• You hold a Bachelor’s or Master’s degree in a scientific or technical discipline — life sciences, data management, or a related field


• You have at least 10 years of experience in clinical data management within the pharmaceutical, biotechnology, or healthcare industry, including substantial leadership of complex oncology, neurology, or immunology trials at study and program level.


• You bring deep expertise in end-to-end data management, including risk-based data collection and cleaning strategies, eCRF design, external data management, and coding, with strong knowledge of CDISC, CDASH, and SDTM standards.


• You have a proven track record of managing CRO/vendor relationships, including operational performance oversight and budget monitoring, and are experienced in in-house sourcing models.


• You are skilled at leading and coordinating global, cross-functional teams in a matrix environment, and are confident providing updates on study progress, financials, forecasts, risks, issues, and timelines to senior stakeholders.


• You demonstrate strong project management capabilities — planning study timelines and resources, identifying and mitigating risks, resolving issues, and managing multiple priorities simultaneously with a high degree of independence.


• You are committed to continuous improvement and bring external insights to contribute to innovation, process development, and the evolution of data management standards and SOPs.


• Experience with Risk Based Data Monitoring and Management is preferred. Experience evaluating or implementing automation and/or AI-enabled innovations in clinical data management, with an understanding of data quality, traceability, validation, human oversight, and compliance considerations, is an advantage.

What we offer

• Money makes the world go round. But at our company there’s more than just financial rewards. We offer a range of attractive benefits to help you work your magic.


• Our 401(k) Plan includes a generous company-matching contribution and an additional discretionary contribution each year.


• We also provide tax-advantaged accounts for you to save for healthcare, commuting expenses, company-provided and buy-up life insurance to help you protect your financial future.


• We offer comprehensive medical, dental, & vision coverage-including virtual care through Telehealth & free behavioral health counseling sessions through our Employee Assistance Program.


• We also offer a wellness incentive program and personalized support to help you navigate and use your benefits.


• Our voluntary benefits provide additional protection from the high costs of healthcare not covered by health insurance.


• We also have discount programs that offer exclusive savings on everything from auto, home, and pet insurance to low-interest personal loans.


• We have several programs to support your work/life balance, including generous paid time off, back-up day care services, education assistance, and more.

US Equal Employment Opportunities

The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.

Associate Director Clinical Data Manager • Feltham, London, United Kingdom