Senior Manager, Clinical Data Management

Bristol Myers Squibb; Denham; Hybrid; GBP 90,000 - 120,000; Full time

Job summary

Bristol Myers Squibb is seeking a Senior Manager of Clinical Data Management to lead end-to-end data management for complex trials, partnering with internal teams and external partners to ensure high-quality data and timely delivery.

You will shape data systems, own quality plans, and mentor junior leads while collaborating across regulatory, safety, and operations to support inspections and submissions.

Qualifications

• Bachelor's degree in a life sciences field is required.
• Hands-on experience with FDA/ICH guidelines and data management best practices.
• Experience with EDC systems; Medidata RAVE experience is a strong plus.
• PMP certification is a bonus and helps with project management.
• Ability to translate complex data into clear insights through metrics and reporting.
• Outstanding communication skills and ability to work with senior leadership and vendors.
• Familiarity with NDA, BLA, and MAA submission processes.

Responsibilities

• Lead end-to-end clinical data management across complex trials with internal and external partners.
• Own data management lifecycle from planning to submission-ready datasets delivered on time.
• Shape trial systems, gather requirements for EDC platforms and collaborate with eCOA, External Data, and Safety Gateway.
• Chair Data Quality Review meetings to ensure audit-ready data.
• Develop and review Data Quality Management Plans, Data Validation Plans, eCRF Guidelines.
• Mentor junior Data Management Leads and raise team capability.
• Represent DM in cross-functional teams and regulatory submissions; support inspections.
• Oversee vendor relationships and SLAs to protect data integrity.
• Drive CAPA and continuous improvement initiatives.

Skills

Leadership experience

Data quality mindset

Stakeholder management

Communication skills

Education

Bachelor's degree in a relevant field

Tools

EDC systems

Medidata RAVE

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Location: Uxbridge

Hybrid Working 50% on site

Are you ready to do the work of your career?

At Bristol Myers Squibb, we believe that the right data, in the right hands, at the right time can change everything. Every clinical trial we run brings us closer to a treatment that could transform or save a patient's life.

As our Senior Manager of Clinical Data Management, you'll be the person who makes that possible.

This isn't just a data role. It's a leadership position at the heart of our R&D pipeline; where your decisions, your standards, and your expertise directly shape the speed and quality of life-changing medicines reaching patients worldwide.

What You’ll Be Doing

Leading Where It Matters Most

You’ll take the wheel on end-to-end clinical data management for some of our most complex and impactful trials. That means being the go‑to person for both internal teams and external partners, the one who sets the bar for data quality and makes sure everyone clears it.

• Drive data collection strategy across one or more complex clinical development projects, aligning cross-functional teams around clear, high-quality standards
• Own the full data management lifecycle, from planning and collection through to clean, submission-ready datasets delivered on time
• Shape the systems that power our trials, leading requirements gathering for EDC platforms and collaborating with partners across eCOA, External Data, and Safety Gateway
• Chair Data Quality Review meetings to keep trial data current, complete, and audit-ready at every stage
• Author and review key study documents, Data Quality Management Plans, Data Validation Plans, eCRF Completion Guidelines and more, ensuring consistency and compliance across the board

Mentoring the Next Generation

• One of the most rewarding parts of this role? You’ll coach and guide junior Data Management Leads, helping them grow while raising the overall capability of the team. Your expertise becomes their foundation.

Representing DM at the Highest Level

• You’ll sit at the table for cross‑functional project teams and regulatory submission teams, and you’ll be a key player during Health Authority inspections and audits. This is a role where your voice carries real weight.

Vendor Oversight & Partnerships

• Whether working with FSPs, CROs, or third‑party vendors, you’ll be the quality compass; monitoring deliverables, managing data currency throughout the trial, and holding partners accountable to SLAs that protect the integrity of our work.

Driving Continuous Improvement

• You’ll contribute meaningfully to how we evolve as an organisation — supporting CAPA implementation and bringing fresh thinking to continuous improvement initiatives within Clinical Data Management.

What’s In It For You

• Meaningful impact, your work directly supports the development of medicines that matter to millions of patients globally
• Career elevation, step into a senior leadership role with visibility across R&D and a clear path toward Director‑level progression
• Cross‑functional influence, build relationships across clinical operations, regulatory, biostatistics, and beyond
• Industry exposure, travel to conferences, investigator meetings, and regulatory engagements (approximately 5–10% travel) to stay at the forefront of your field
• Intellectual challenge, work with cutting‑edge data collection technologies and emerging industry trends that keep your skills sharp and future‑proof

What You’ll Bring

• A Bachelor's Degree (advanced degree preferred) and at least 5 years of relevant industry experience
• A strong command of clinical drug development processes, FDA/ICH guidelines, and data management best practices
• Hands‑on experience with EDC systems; Medidata RAVE experience is a strong plus
• Proven project management skills, with a PMP certification considered a bonus
• The ability to translate complex data into clear insights through metrics analysis and reporting
• Outstanding communication skills, whether you’re presenting to senior leadership or collaborating with a vendor team, you know how to land the message
• Familiarity with submission requirements including NDA, BLA, and MAA processes

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models site-essential, site-by-design, field-based and remote‑by‑design. The model assigned to this role is based on its core responsibilities. Learn more at https //careers.bms.com/ways-of-working.

Supporting People With Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Bristol Myers Squibb is Disability Confident – Employer

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information https //careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https //careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application‑related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1603294 Senior Manager, Clinical Data Management