AI/ML Postdoctoral Fellow-Spatial Genomics & Liver Disease

The Francis Crick Institute; Greater London; On-site; GBP 43,000 - 52,000; Full time

Benefits offered by this job

Visas sponsorship

28 days annual leave

Pension scheme

On-site restaurant discounts

Job summary

The Francis Crick Institute in the United Kingdom is seeking an ambitious AI/ML Postdoctoral Fellow to lead a computational project in the TRCE Lab, focusing on how driver mutation clones interact with their microenvironment in liver disease and liver cancer.

Embedded across Crick and Sanger, you will collaborate with clinicians and computational scientists, applying state-of-the-art machine learning to large-scale spatial genomics and multi-modal data, with opportunities for high-impact

Qualifications

• PhD (or near submission) in computational biology, machine learning, computer science, statistics or a related quantitative discipline.
• Experience developing and applying deep learning or AI/ML methods to complex scientific datasets.
• Strong programming and scientific computing skills in Python (e.g. numpy, pandas, PyTorch and/or JAX).
• Experience analysing complex biological, imaging or spatial datasets, or strong evidence of rapidly adapting to new data domains.
• Excellent communication, organisational and collaborative working skills.
• Ability to work effectively within interdisciplinary and cross-institutional research teams.

Responsibilities

• Developing advanced AI/ML methods for analysing spatial genomics and histology datasets.
• Applying graph neural networks, transformer models and generative AI approaches to study clone-microenvironment interactions.
• Integrating spatial transcriptomics, single-cell sequencing and imaging datasets.
• Designing benchmarking strategies and reproducible computational workflows.
• Performing clonal reconstruction and spatial mapping analyses from genomic datasets.
• Collaborating closely with computational scientists, clinicians and experimental researchers across the Crick and Sanger Institute.
• Leading publications, conference presentations and dissemination of research findings.

Job description

The Francis Crick Institute in the United Kingdom is seeking an ambitious AI/ML Postdoctoral Fellow to lead a computational project in the TRCE Lab, focusing on how driver mutation clones interact with their microenvironment in liver disease and liver cancer.

Embedded across Crick and Sanger, you will collaborate with clinicians and computational scientists, applying state-of-the-art machine learning to large-scale spatial genomics and multi-modal data, with opportunities for high-impact