ADME/DMPK Technical Expert – PK/TK & CRO Lead

Syngenta Crop Protection; Bracknell; On-site; GBP 65,000 - 95,000; Full time

Benefits offered by this job

Extensive benefits package including a

Up to 31.5 days annual holiday

Job summary

Syngenta Crop Protection in the UK is seeking an experienced DMPK/ADME Technical Expert to join the Analytical Metabolism and Methods group. You will design innovative ADME/PK studies and support registration of crop protection products.

Collaborating with CROs and internal toxicology and metabolism teams, you will interpret ADME/PK/TK data, ensure GLP-compliant study delivery, and provide regulatory insights to optimise study designs and timelines.

Qualifications

• Degree in biology or chemistry or related discipline.
• Significant knowledge in DMPK/ADME with PK/TK expertise.
• Familiarity with global Regulatory Test Guidelines (e.g. OECD 417) relevant to ADME and toxicokinetics studies conducted to GLP standards for the registration of crop protection chemicals.
• Experience translating complex datasets into key safety or regulatory insights to inform decision making.
• Practical knowledge of quantitative PK/TK principles, including non-compartmental analysis (NCA).
• Proven ability to collaborate within diverse scientific teams and with external stakeholders to achieve project goals.
• Ability to organise, prioritise, and track complex scientific deliverables with attention to detail.

Responsibilities

• Overseeing CRO delivery and study strategy documents.
• Delivering technical insights from ADME and PK/TK data.
• Applying regulatory guidance and updating study designs.
• Partnering with CROs and external suppliers to enable study transfer.
• Driving creation and optimisation of new processes and templates.
• Serving as scientific contributor within the ADME/PK/TK area.

Skills

DMPK/ADME expertise

Pharmacokinetics

Toxicokinetics

Regulatory guidelines knowledge

Data translation to safety insights

PK/TK analysis (NCA)

Education

Biology or Chemistry degree

Job description

Syngenta Crop Protection in the UK is seeking an experienced DMPK/ADME Technical Expert to join the Analytical Metabolism and Methods group. You will design innovative ADME/PK studies and support registration of crop protection products.

Collaborating with CROs and internal toxicology and metabolism teams, you will interpret ADME/PK/TK data, ensure GLP-compliant study delivery, and provide regulatory insights to optimise study designs and timelines.