Scientist / Research Engineer

Gustave Roussy Cancer Campus; France; Sur place; EUR 35 000 - 45 000; Plein temps

Résumé du poste

A leading cancer research institution seeks a highly motivated scientist to join their research team. The role focuses on studying chromatin remodeling defects in cancer, requiring a PhD in cancer biology or immuno-oncology and expertise in proteomics. Candidates should have experience with techniques like ChIP-Seq, ATAC-Seq, and CRISPR-Cas9. This position offers an opportunity to work in a collaborative environment at a top-tier cancer research center in France.

Qualifications

• PhD in cancer biology or immuno-oncology, and at least 2 years of experience post-PhD.
• Expertise in proteomics is required.
• Background in epigenetics with experience in relevant techniques.
• Experience in molecular biology and genome editing.
• Experience in single-cell technologies.
• Willingness to get a mouse license is desirable.
• Experience in bioinformatics and NGS analysis is a plus.

Responsabilités

• Design and execute experiments to explore chromatin remodeling in cancer.
• Collaborate with the Drug Development Department.
• Work in a dynamic research environment.

Connaissances

Proteomics

ChIP-Seq

ATAC-Seq

RNA-Seq

CRISPR-Cas9

Single-cell technologies

Bioinformatics

Formation

PhD in cancer biology or immuno-oncology

Description du poste

Organisation/Company Gustave Roussy Cancer Campus Department Drug Development department Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country France Application Deadline 1 Nov 2025 - 23:59 (Europe/Paris) Type of Contract Temporary Job Status Full-time Hours Per Week 35 Offer Starting Date 1 Nov 2025 Is the job funded through the EU Research Framework Programme? Other EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are seeking for a highly motivated scientist / research engineer to join the team of Sophie Postel-Vinay at Gustave Roussy, to work on an exciting project studying chromatin remodeling defects and epitranscriptomics in cancer, selected for funding by the European Research Council (ERC) and as part of the Gustave Roussy Integrated Research Centre (SIRIC) institutional program .

Context: The (Epi)genetic Vulnerabilities of Solid Tumours and Sarcoma lab, led by Dr Sophie Postel-Vinay as part of the Gustave Roussy Inserm Unit U981, aims to investigate synthetic lethal interactions as new therapeutic strategies for tumours defective in DNA repair or epigenetic processes . Our team closely collaborates with theDrug Development Department and the sarcoma committee, to validate molecular predictors and implement new targets in therapeutic trials. The candidate will be supervised by S. Postel-Vinay and have the opportunity to work in an extremely dynamic and collaborative research environment at Gustave Roussy, one of the leading cancer research centers in Europe, in close collaboration with other French and international excellent institutions, notably the University College of London Cancer Institute.

Objectives: The aim of the project is to study chromatin remodeling defects in cancer. The successful candidate will be responsible for designing and executing experiments to explore chromatin remodeling in selected tumor types, using preclinical models and molecular data from patients’ tumor samples.

Required skillset:Applicants are expected to have the following:

• PhD in cancer biology or immuno-oncology, and at least 2 years of experience after PhD;
• Expertise in proteomics is required;
• Background in epigenetics, with solid experience in techniques such as ChIP-Seq, ATAC-Seq, RNA-Seq, Cut&Tag or Cut&Run;
• Background in molecular biology and genome editing (e.g. CRISPR-Cas9);
• Experience in single-cell technologies;
• Mouse license (or willingness to get one) is desirable;
• Experience in bioinformatics and analysis of NGS or single-cell data (or willing to learn such analyses);