Project Manager / Project Leader – Discovery & Preclinical Programs

Valerio Therapeutics

Paris

On-site

EUR 90,000 - 130,000

Full time

14 days+

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Benefits offered by this job

Annual bonus

Vélib subscription covered

Family health insurance

Job summary

Valerio Therapeutics is seeking a Project Manager / Project Leader to oversee and drive discovery and preclinical programs. You will coordinate cross-functional teams to deliver milestones, reporting to the VP of Discovery & Preclinical.

The ideal candidate brings 10+ years of biotech project leadership and deep immunology expertise, especially in inflammatory and autoimmune diseases. You will guide early discovery through preclinical nomination, manage timelines, risks, and budgets, and ensure

Qualifications

Advanced degree (PhD) in Immunology, Molecular Biology, or related life sciences.
10+ years of experience in biotech as project manager or program leadership roles.
Strong scientific background in immunology, with focus on inflammatory and autoimmune diseases.
Solid understanding of biologics R&D, ideally with exposure to antibody-based therapeutics and oligonucleotide.
Proven ability to manage cross-disciplinary projects in a matrixed and dynamic environment.
Strong organizational, communication, and leadership skills.
Proficiency with project management tools (MS Project, Smartsheet, Excel, PowerPoint).
PMP or equivalent certification is a plus but not required.

Responsibilities

Lead internal R&D project teams through early discovery to preclinical candidate nomination.
Develop and maintain detailed project plans, timelines, and risk registers.
Coordinate input and deliverables from cross-functional stakeholders (e.g., antibody engineering, biology, pharmacology, CMC).
Facilitate team meetings, track action items, and ensure alignment with strategic objectives.
Monitor project progress, budgets, and resource allocation.
Identify scientific or operational risks and propose mitigation strategies.
Provide regular project updates and decision-making support to the VP and executive team.
Ensure clear documentation, data tracking, and reporting across internal programs.
Encourage a transversal mindset driven by collective curiosity and learning.

Skills

Project management

Immunology

Cross-functional leadership

Biologics R&D

Antibody therapeutics

Oligonucleotides

PMP

MS Project

Smartsheet

Excel

PowerPoint

Education

PhD in Immunology

PhD in Molecular Biology

Tools

MS Project

Smartsheet

Excel

PowerPoint

Job description

Project Manager / Project Leader – Discovery & Preclinical Programs

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Project Manager / Project Leader – Discovery & Preclinical Programs

We are an innovative biotech company specializing in the development of next-generation therapeutics (single-domain antibodies, conjugates, siRNA, etc.). Our agile and passionate R&D team works on cutting-edge projects in immunology, oncology, and rare diseases.

Job Summary

We are seeking a Project Manager / Project Leader to oversee and drive the execution of internal discovery and preclinical programs. This role is pivotal in coordinating cross-functional efforts, ensuring alignment with scientific and strategic goals, and enabling project teams to deliver on key milestones. The ideal candidate will bring over 10 - 15 years of experience in biotech, strong project management capabilities, and deep expertise in immunology, particularly in inflammatory and autoimmune diseases. The role reports directly to the VP, Discovery & Preclinical.

Keys responsabilities :

Lead internal R&D project teams through early discovery to preclinical candidate nomination
Develop and maintain detailed project plans, timelines, and risk registers
Coordinate input and deliverables from cross-functional stakeholders (e.g., antibody engineering, biology, pharmacology, CMC)
Facilitate team meetings, track action items, and ensure alignment with strategic objectives
Monitor project progress, budgets, and resource allocation
Identify scientific or operational risks and propose mitigation strategies
Provide regular project updates and decision-making support to the VP and executive team
Ensure clear documentation, data tracking, and reporting across internal programs
Encourage a transversal mindset driven by collective curiosity and learning

Qualifications & Experience required

Advanced degree (PhD) in Immunology, Molecular Biology, or related life sciences
10+ years of experience in biotech as project manager or program leadership roles
Strong scientific background in immunology, with a particular focus on inflammatory and autoimmune diseases
Solid understanding of biologics R&D, ideally with exposure to antibody-based therapeutics and oligonucleotide
Proven ability to manage cross-disciplinary projects in a matrixed and dynamic environment
Strong flexible organizational, communication, and leadership skills
Proficiency with project management tools (e.g., MS Project, Smartsheet, Excel, PowerPoint)
PMP or equivalent certification is a plus but not required

Our Values :

Scientific curiosity: Ability to explore complex topics with a proactive, solution-oriented mindset and strong problem-solving skills.
Rigor and analytical mindset: Methodical approach, critical thinking when interpreting experimental data, with strong attention to detail and reproducibility.
Team spirit: Close collaboration with R&D teams, respect for complementary expertise, and clear, constructive communication.
Scientific integrity: Adherence to protocols, transparency in results, and a strong ethical commitment throughout the project.
Adaptability: Agility in a fast-evolving environment, ability to handle unexpected challenges, and continuous learning from both successes and failures.
Passionate about translating science into impact for patients
Annual individual performance bonus
100% coverage of Vélib bike subscription
60% coverage of family health insurance plan
Exciting, high-impact scientific projects
Supportive and dynamic work environment
Small, agile team with real responsibilities from day one
Modern offices, state-of-the-art equipment… and unlimited coffee!