Preclinical R&D Scientist - Drug Development

Obsidian; Paris; Sur place; EUR 15 000 - 30 000; Temps partiel

Résumé du poste

Mercor is seeking a hands-on preclinical R&D scientist to guide AI-driven drug discovery platforms. You’ll blend wet-lab and translational experience with data-driven modeling to inform target selection, modality decisions, and pipeline structure.

You’ll work closely with a partner pharma client and contribute to dataset standards and model feedback loops. The role is part-time (about 10 hours/week) and suitable for candidates with 5+ years in preclinical R&D across modalities, from small

Qualifications

• Must have hands-on preclinical R&D experience at a company that develops its own drug assets in-house and has taken programs to the clinic.
• Work in a core R&D function: discovery biology, medicinal chemistry, protein/antibody engineering, computational, in vivo/translational, pharmacology/PK-PD, toxicology, or CMC/formulation.
• Hands-on experience with one or more drug modalities (small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, radioligand therapies, etc.).
• Have 5+ years of relevant industry R&D experience (flexible based on depth).
• Have taken a program through lead optimization or IND-enabling/preclinical development (nice to have).
• Have experience at mid-sized, emerging, or resource-constrained biotech - ideally currently outside the top-20 pharmaceutical companies (nice to have).

Responsabilités

• Review technical materials and real-world R&D data in your area of expertise.
• Label, classify, and annotate scientific data and model outputs to improve model performance.
• Provide expert perspective on key scientific and development decisions (target/modality selection, optimization, trade-offs, risk).
• Help define structure and quality standards for the client's dataset pipeline.
• Participate in expert discussions, interviews, and research engagements.

Connaissances

Preclinical R&D

Discovery biology

Medicinal chemistry

Protein/antibody engineering

Computational

Pharmacology/PK-PD

Toxicology

CMC/formulation

Description du poste

Mercor is partnering with a venture-backed AI lab building frontier AI platforms and physics-based foundation models for chemistry, materials science, and drug discovery. They're extending their platform into new areas of pharmaceutical development and are looking for hands-on preclinical R&D experts across drug modalities to help guide what they build.

Are you a preclinical R&D scientist who has taken drug programs from the bench toward the clinic - and curious how AI is reshaping drug discovery? This is a hands-on role that blends your wet-lab and translational experience with a growing understanding of how scientific data trains the next generation of AI models.

In this role, you'll:

• Review technical materials and real-world R&D data in your area of expertise
• Label, classify, and annotate scientific data and model outputs to improve model performance
• Provide expert perspective on key scientific and development decisions (target/modality selection, optimization, trade-offs, risk)
• Help define structure and quality standards for the client's dataset pipeline
• Participate in expert discussions, interviews, and research engagements

You're a strong fit if you:

• Have hands-on, non-administrative preclinical R&D experience at a company that develops its own drug assets in-house and has taken programs to the clinic - Must Have
• Work in a core R&D function: discovery biology, medicinal chemistry, protein/antibody engineering, computational, in vivo/translational, pharmacology/PK-PD, toxicology, or CMC/formulation - Must Have
• Have hands-on experience with one or more drug modalities (small molecules, monoclonal antibodies, peptides, ADCs, bispecifics, mRNA, siRNA, ASOs, PROTACs, molecular glues, cell therapies, gene therapies, radioligand therapies, etc.) - Must Have
• Have 5+ years of relevant industry R&D experience (flexible based on depth)
• Have taken a program through lead optimization or IND-enabling/preclinical development (nice to have)
• Have experience at mid-sized, emerging, or resource-constrained biotech - ideally currently outside the top-20 pharmaceutical companies (nice to have)

This is a hands-on preclinical R&D role - likely not the right fit if your work is mainly CRO/CDMO services, academic-only, QC/analytical-only, clinical-development-only, diagnostics, or regulatory/medical-writing.

Your work will directly feed into the models reshaping how medicines are discovered, helping intelligent systems reason about real-world pharmaceutical R&D.

Here are more details about the role:

• You will interface directly with the client team.
• This is an ongoing, part-time engagement of roughly 10 hours per week.
• Seniority welcome from individual contributor through Director.