Postdoctoral Scientist: Mechanobiology & Spatial Omics

Gustave Roussy; France; Presencial; EUR 36.000 - 48.000; Jornada completa

Descripción de la vacante

The Tumor Dynamics and Plasticity group at Institut Gustave Roussy (Villejuif, Paris) seeks a highly motivated postdoctoral researcher with a PhD in quantitative biology or bioinformatics. You will develop multidisciplinary research bridging tissue mechanics and transcriptomics, building pipelines to combine organoid force measurements with spatial omics.

Ideally, you will have wet- and dry-lab interest; wet-lab experience is not required.

Formación

• PhD or equivalent required.
• Experience in quantitative biology and bioinformatic analysis preferred.

Responsabilidades

• Develop pipelines to combine organoid force measurements with spatial omics.
• Bridge tissue mechanics and transcriptomics across wet- and dry-lab approaches.
• Collaborate within a multidisciplinary team to study tumor dynamics and plasticity.

Conocimientos

Quantitative biology

Bioinformatics

Image analysis

Spatial transcriptomics

Educación

PhD or equivalent

Descripción del empleo

Biological sciences » Biological engineering

Engineering » Biomedical engineering

Computer science » Programming

Organisation/Company Gustave Roussy Department INSERM U1279 Research Field Biological sciences » Biological engineering Physics » Biophysics Engineering » Biomedical engineering Computer science » Programming Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Application Deadline 15 Nov 2026 - 23:59 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Horizon Europe - ERC Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The“Tumor Dynamics and Plasticity” group is a newly established research team atInstitut Gustave Roussy (Villejuif, Paris), led by Carlos Pérez-González. Our goal is to understand how mechanochemical signals regulate tumor cell state patterning and how these processes drive tumor progression and clinical outcome.

With the help of our recent ERC Starting Grant, we are building a multidisciplinary team at the interface of biology and physics, integrating mechanobiology, quantitative imaging and transcriptomics in organoids and tumors. Located within the largest cancer hospital in Europe, our lab benefits from access to patient-derived organoids, clinical samples, and oncology expertise.

We are seeking a highly motivated postdoctoral researcher with expertise in quantitative biology or bioinformatics. The candidate will develop multidisciplinary research bridging tissue mechanics and transcriptomics, with the goal of understanding how mechanical signals guide cancer cell plasticity. The project will involve developing pipelines to combine organoid force measurements with spatial omics approaches. Ideally, the candidate should be interested in both wet- and dry-lab research, but wet-lab experience is not required.

Where to apply

E-mail [e-mail]

Requirements

Research Field Physics » Biophysics Education Level PhD or equivalent

Research Field Biological sciences » Biological engineering Education Level PhD or equivalent

Skills/Qualifications

Ideally, the candidate has experience in quantitative biology and bioinformatic analysis, including:

• Image analysis (cell segmentation, tracking, morphometry analysis)
• Spatial transcriptomics

Our ambition is to create a supportive, inclusive, and stimulating research environment where scientific curiosity thrives. We value collaboration, intellectual rigor, and creativity, and we are committed to fostering a positive atmosphere in which team members can grow scientifically and personally.

• Contact details of references who can provide recommendations

All applicants will be notified of the outcome after the application deadline.