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Nantes Université is seeking a motivated postdoctoral researcher with a PhD in bioprocess engineering or related field to join the Bioprocess Applied to Microalgae team at the GEPEA Laboratory. The candidate will develop a scalable microfluidic system for organoid culture and processing, working closely with the Nantes Organoid Infrastructure to optimize hydrodynamics and assess cell viability.
The role involves designing, setting up, and operating the lab platform, conducting experiments to
Organisation/Company Nantes Université Research Field Biological sciences Researcher Profile First Stage Researcher (R1) Application Deadline 25 Oct 2026 - 00:00 (UTC) Type of Contract Temporary Job Status Full-time Hours Per Week 35.0 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number 19k7y8w6v7 Is the Job related to staff position within a Research Infrastructure? No
Nantes Université is currently seeking an enthusiastic and motivated postdoctoral researcher with a PhD related to bioprocess engineering development to join the "Bioprocess Applied to Microlgae" team at the GEPEA Laboratory.
The successfull candidate will contribute to the development of a microfluidic system for the culture and processing of human organoids used in biomedical research. Currently, organoid dissociation and homogenization rely on time-consuming and poorly reproducible manual procedures, representing a major bottleneck for scale-up, inter-laboratory comparability, and automation of organoid preparation and culture workflows.
The proposed microfluidic process, designed to be readily scalable, will enable gentle and controlled organoid fragmentation, ensuring a homogeneous size distribution while preserving cell viability. Experimental studies will be conducted in close collaboration with the Nantes Organoid Infrastructure (UMS BioCore-ION), which specializes in human organoid cultures, to identify optimal hydrodynamic operating conditions and evaluate the impact of the treatment on organoid size, viability, and cellular functionality.
The candidate will be responsible for designing, setting up, and operating the laboratory-scale experimental platform.
The candidate will conduct the experimental work required to demonstrate the proof of concept of the developed microfluidic system.
To achieve these objectives, the candidate will benefit from the facilities, equipment, and technical resources available at the GEPEA Laboratory, as well as from the project budget allocated to specific project needs.
In addition, the candidate will be responsible for project reporting activities, including the preparation of technical reports, supporting documentation, and project deliverables.
More generally, they will contribute to the day-to-day management and coordination activities necessary for the successful implementation of the project:
Expected level of qualification: PhD or equivalent. The candidate must hold a PhD in bioprocess engineering, biotechnology, microbiology, or in a field closely related to microalgae and sustainable production processes.
Expertise in the field of bioprocesses applied to microalgae would be an additional asset.
Skills and qualifications required: Adaptability, autonomy, ability to cooperate, ability to research and evaluate information.
Specific skills: Culture or co-culture of microorganisms. Ability to culture in bioreactors. Experience in designing experimental systems is welcome.
Languages: French and a good level of English (B2-C1)