Postdoc: Photochemical Synthesis of Anticancer Agents

CNRS; France; On-site; EUR 20,000 - 25,000; Full time

Job summary

The Laboratoire Lorrain de Chimie Moléculaire (CNRS) in France seeks a PhD-qualified researcher to join the SAMPA group. You will lead organic synthesis projects, manage a compound library, and collaborate across chemistry, biology, and theory teams to advance photoactive compounds.

Applicants should hold a PhD in Organic Chemistry, have strong hands-on synthesis and purification skills, and demonstrate excellent communication and mentoring abilities.

Qualifications

• PhD in Organic Chemistry obtained within the past two years with extensive experience in organic synthesis, purification techniques, and chemical characterization methods.
• Experience in photochemistry would be an asset.
• Ability to work independently, proactive attitude, and collaborate effectively within a multidisciplinary team.
• Excellent oral and written scientific communication skills, including the ability to present research findings and write scientific publications.
• Strong interest in and aptitude for supervising and mentoring students.

Responsibilities

• Set up a library of compounds to be prepared and define priority order.
• Achieve multi-steps syntheses to get the desired final compounds.
• Purify efficiently all these compounds and achieve complete physico-chemical characterization.
• Achieve photochemical characterization of the final compounds absorption maxima, fluorescence (fluorescence quantum yield).
• Measure photochemical conversion kinetics by means of 1H-NMR and UV-Vis spectroscopy
• Manage the library of compounds and ensure their transmission to biologists. Gather and analyze structure-activity relationships.
• Work with theoretical chemists partners in order to 1) Understand structure/absorption maxima relationships, 2) Decipher mechanisms involved in photochemical reactions, and 3) discover the chemical interactions between molecules and the biological target.

Skills

Organic synthesis

Purification techniques

Chemical characterization

Supervising students

Scientific communication

Education

PhD in Organic Chemistry

Job description

The Laboratoire Lorrain de Chimie Moléculaire (CNRS) in France seeks a PhD-qualified researcher to join the SAMPA group. You will lead organic synthesis projects, manage a compound library, and collaborate across chemistry, biology, and theory teams to advance photoactive compounds.

Applicants should hold a PhD in Organic Chemistry, have strong hands-on synthesis and purification skills, and demonstrate excellent communication and mentoring abilities.