Photonic microscopy engineer

France-BioImaging; Montpellier; Sur place; EUR 32 000 - 42 000; Plein temps

Résumé du poste

BioImaging and Pathologies Laboratory in Illkirch-Graffenstaden (France) is seeking a Research Engineer for a 12-month position within the BIMC team, at the interface of biophysics, biology and chemistry.

The role focuses on developing a laser-based imaging setup, validating performance on a benchmark chromophore, and building data analysis pipelines to quantify TRAST dynamics, contributing to infection biology and epigenetic regulation research.

Qualifications

• Hands-on experience with photonic spectroscopy hardware.
• Solid understanding of optical alignment and beam propagation principles.
• Proficiency in at least one programming environment: MATLAB, Python, LabVIEW or Arduino.
• Familiarity with fluorescence microscopy data processing.
• Basic knowledge of (bio)molecular systems and their photophysics.
• English proficiency at B2 level (or higher).

Responsabilités

• Instrumental development – Assemble and align a complete laser based setup (laser sources, AOM, beam delivery optics, and sCMOS camera detector).
• Instrument Validation – Demonstrate performance with a benchmark chromophore that populates dark states (e.g., Cy5).
• Data analysis pipeline – Develop and document software tools for real-time TRAST data acquisition and analysis.

Connaissances

Photonic spectroscopy hardware

Optical alignment

Programming (MATLAB)

Programming (Python)

Programming (LabVIEW)

Arduino

Fluorescence microscopy data

Biophysics basics

English (B2)

Outils

MATLAB

Python

LabVIEW

Arduino

Description du poste

Organization: BioImaging and Pathologies Laboratory

Location: 74 Route du Rhin, Illkirch-Graffenstaden, France

Position Information

The BioImaging and Pathologies Laboratory (LBP) is recruiting a Research Engineer for a 12-month position within the Biophotonics of Molecular and Cellular Interactions (BIMC) team. At the interface of biophysics, biology and chemistry, BIMC develops advanced fluorescence-based approaches to study biomolecular interactions involved in infection and epigenetic regulation.

Main missions

• Instrumental development – Assembly and align a complete laser based set-up (laser sources, AOM, beam delivery optics, and sCMOS camera detector),
• Instrument Validation – Demonstrate performance with a benchmark chromophore that populates dark states (e.g., the photo isomerisation dynamics of the pentamethine cyanine Cy5),
• Data analysis pipeline – Implement, test and document software tools for real time acquisition and quantitative analysis of TRAST data.

Profile

Required knowledges

• Hands-on experience with photonic spectroscopy hardware (lasers, modulators, detectors),
• Solid understanding of optical alignment and beam propagation principles.
• Proficiency in at least one programming environment: MATLAB, Python, LabVIEW or Arduino,
• Familiarity with fluorescence microscopy data processing,
• Basic knowledge of (bio)molecular systems and their photophysics,
• English proficiency at B2 level (or higher).

Desired Skills And Personal Qualities

• Precision and rigor in experimental work; strong troubleshooting mindset,
• Ability to write clear user protocols and to contribute to scientific publications,
• Good visual and oral presentation skills,
• Proven team spirit and ability to collaborate effectively within a multidisciplinary group.