ONE BIOSCIENCES – Molecular Biology Lab Technician

ESTBA; Paris; Sur place; EUR 38 000 - 50 000; Plein temps

Résumé du poste

A pioneering precision diagnostics firm in Paris is seeking a Molecular Biology Lab Technician to carry out single-cell omics data generation pipelines. You will be responsible for organizing sample reception, performing library preparations, and assisting the research team on new experiments. Applicants should have a BTS or DUT in Bioanalyses/Biotechnologies, network with human samples and demonstrate strong skills in molecular biology. Join our mission to revolutionize cancer diagnostics.

Qualifications

• At least two years of proven experience in Molecular Biology.
• Experience on a genomics and/or sequencing platform.
• Familiarity with quality standards (ISO 15189, ISO 17025, GLP, etc.) is appreciated.

Responsabilités

• Organise human sample reception and perform library preparation.
• Prepare and launch sequencing runs and report results.
• Assist in development and validation of new multi-omics experiments.
• Monitor stocks, orders, and equipment maintenance.

Connaissances

Library preparation for NGS

DNA and RNA extraction

qPCR/RT-PCR

Fluorescence microscopy

Single-cell experiments (10X)

Team collaboration

Attention to detail

Formation

BTS or DUT/BUT in Bioanalyses/Biotechnologies

Outils

NGS (Illumina)

EpiMotion

Mosquito

Bioanalyzer or Tapestation

Description du poste

ONE BIOSCIENCES – Molecular Biology Lab Technician

Full time employee position. Location: Paris (offices in Biolabs, 75014).

About One Biosciences: One Biosciences is a pioneering precision diagnostics company uniquely positioned to decipher tumor heterogeneity through the convergence of single‑cell transcriptomics and artificial intelligence. Our proprietary platform combines cutting‑edge biological protocols, advanced algorithms, and molecular signatures to deliver clinical‑grade insights that transform cancer treatment decisions. Leveraging proprietary and public single‑cell datasets in oncology, our technology enables healthcare providers to understand the complex cellular landscape of tumors with unprecedented precision and speed. We have established strategic partnerships with leading French cancer centers including Institut Curie and Gustave Roussy, while preparing an expansion in the US market through collaborations with top‑tier institutions. Following our successful €14 M Series A funding round led by prominent investors, One Biosciences is scaling globally to bring the next generation of precision diagnostics to oncologists and pharmaceutical companies worldwide. Join us in our mission to revolutionise cancer care by unlocking the secrets hidden within every single cell.

The Context: As we scale our operations globally and expand our partnerships from Europe to the US, we are entering a critical phase where we need to increase our capabilities in terms of output in the wetlab to manage more and larger projects. As part of this strategic evolution, the lab technician will be responsible to work in the lab to process samples from raw material to sequencing.

Responsibilities

• Carry out and ensure the completion of single‑cell omics data generation pipelines in a standardized fashion:
  • Organise human sample reception (Frozen and/or FFPE)
  • Perform library preparation (10X Genomics)
  • Implement PCR/qPCR techniques, purification, dosage and quality control
  • Prepare and launch sequencing runs (NGS‑Illumina)
  • Report results autonomously and clearly (Labguru)
• Assist the research team in development and validation of new multi‑omics experiments.
• Assist in monitoring stocks, orders and equipment maintenance.

Qualifications

• Education level
  • BTS or DUT/BUT (Bioanalyses; Biotechnologies; Biological engineering or related disciplines).
  • At least two‑years of proven experience in Molecular Biology.
  • Experience on a genomics and/or sequencing platform.
• Must‑have experience and skills
  • Working on human sample (dissociation/extraction of cells or nuclei) and using microscopy (fluorescence).
  • Molecular biology: library preparation for NGS, bioanalyzer or Tapestation, DNA and RNA extraction, qPCR, RT‑PCR.
  • Experience in single‑cell experiments (10X for instance) and robot dispensers (EpiMotion, Mosquito …) would be particularly appreciated.
  • Familiarity with quality standards (ISO 15189, ISO 17025, GLP, etc.) would be particularly appreciated.
• Non‑technical skills
  • Comfortable with routine laboratory work.
  • Good level in English (reading, writing and speaking).
  • Excellent communications and team working skills.
  • Rigorous; high standards of integrity, accuracy and attention to details.
  • Adaptable, organized, rigorous and results‑oriented.
  • Strong team spirit, taking initiatives to help out others when needed.