Cortex-on-Chip Scientist: Bioengineering & Neurodevelopment

CNRS - National Center for Scientific Research; France; On-site; EUR 26,000 - 32,000; Full time

Job summary

CNRS - National Center for Scientific Research invites applications for a First Stage Researcher (R1) on an ERC Synergy PatCorg project in Paris. The role focuses on developing cortex-on-chip models, delivering morphogens via microfluidics, and analysing cortical regionalisation using imaging and transcription factor gradients.

Candidates should hold a master's degree in biology, bioengineering, biophysics, neuroscience, or microfluidics, with interest in interfacial biology between development

Qualifications

• We are seeking students with a master's degree in biology, bioengineering, biophysics, neuroscience, or microfluidics.
• Experience with stem cells or organoids is a strong plus.
• Knowledge in microfluidics or organs-on-a-chip is beneficial.
• Familiarity with imaging and quantitative analysis is preferred.
• Programming in Python, Fiji/ImageJ, or MATLAB is desirable.

Responsibilities

• Culture and differentiate human pluripotent stem cells into neuroepithelium and cortical organoids.
• Utilize microfluidic devices to deliver morphogens on tissue surfaces.
• Study effects of morphogen concentration and exposure duration.
• Quantify transcription factor gradients and cortical regionalisation.
• Collaborate with PatCorg consortium partners.

Skills

pluripotent stem cells

organoids

microfluidics

neuroscience

microscopy

image analysis

Python

Fiji/ImageJ

MATLAB

Education

Master's degree or equivalent

Tools

μ-transwell devices

Job description

CNRS - National Center for Scientific Research invites applications for a First Stage Researcher (R1) on an ERC Synergy PatCorg project in Paris. The role focuses on developing cortex-on-chip models, delivering morphogens via microfluidics, and analysing cortical regionalisation using imaging and transcription factor gradients.

Candidates should hold a master's degree in biology, bioengineering, biophysics, neuroscience, or microfluidics, with interest in interfacial biology between development