Bioprocess Engineer @InSpek

BREEGA

Paris

Hybride

EUR 45 000 - 65 000

Plein temps

14 jours+

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Avantages offerts par ce poste

Health and life insurance (100%)

Meal vouchers

Gym membership (Gymlib)

Stock options (BSPCE)

Flexible remote work policy

Regular social events

Growth opportunities with leadership

Inclusive culture

Early employee opportunity

Résumé du poste

InSpek in DocCity Suresnes, near Paris, seeks a Bioprocess Engineer to beta test photonic probes in real bioprocess conditions, running small-scale fermentations and monitoring temperature, pH and DO. You will generate well-labelled data to train AI models and support calibration efforts.

The role combines biotechnology and photonics, offering hands-on lab work, documentation, and collaboration across hardware, software, and data teams. Fluency in English is required; French is a plus.

Qualifications

2+ years of bioprocessing experience.
Experience operating bioreactors in batch and fed-batch modes.
Routine lab operations and aseptic techniques.
Inventory management and PPE awareness.
Fluent English; French is a plus.
Familiarity with cGMP and analytical methods.

Responsabilités

Beta test photonic probes in real bioprocess conditions.
Run small-scale fermentations and monitor key parameters.
Calibrate sensors and generate high-quality data.
Document results with traceability for AI model training.
Maintain lab equipment and ensure safe, compliant operations.
Collaborate with hardware/software teams on improvements.

Connaissances

Bioprocessing

Bioreactor operation

Lab operations

Inventory management

Safety procedures

Startup mindset

English fluency

French a plus

Mammalian cell cultures

HPLC/Cedex

Raman spectroscopy

cGMP

Outils

Autoclave

Lab equipment

Description du poste

Who Are We

InSpek uses optical microchip technology to sense multiple molecules, temperature, acidity, oxygenation, and more in real time, directly at the heart of biochemical reactions. Our sensors help produce medicines, food, and energy while reducing waste. We make sensors better, cheaper, and smaller!

Who Are We

Do you want to join a young, dynamic, ambitious, and VC-backed startup?

Then InSpek is the place for you!

What Will You Be Doing

As a Bioprocess Engineer, you will be the first hands‑on user of InSpek’s photonic probes, using them exactly as our future customers will. Within the Applications team, your primary mission is to beta test our probes under realistic bioprocess conditions and to collect high‑quality data to train our AI models. This is a probe‑testing and data‑generation role rather than a process‑optimisation one: you run small‑scale fermentations as the setting in which the probes are challenged, keeping conditions stable and monitoring key parameters such as temperature, pH, and dissolved oxygen so that the data we collect is clean and reliable.

You will conduct measurements using InSpek’s photonic sensors, which will directly contribute to sensor calibration efforts. This position offers a unique opportunity to work at the intersection of biotechnology and photonics, where your hands‑on expertise will support the advancement of next‑generation process monitoring solutions.

Responsabilities

Probe testing:
Act as InSpek’s “first customer”: use and stress‑test the photonic probes in day‑to‑day bioprocess conditions exactly as an end user would
Run structured probe‑testing campaigns covering fouling, cleaning and regeneration, handling, insertion and removal, and robustness over repeated use
Evaluate probe performance across single‑ and multi‑analyte measurements
Document failure modes, usability issues, and improvement ideas, and feed them back to the hardware and software teams
Upstream / fermentation activities:
Prepare and operate small‑scale fermentations using shake flasks and small‑scale bioreactors (primarily yeast to begin with)
Monitor fermentation parameters (temperature, pH, DO, agitation, etc.) and maintain stable, reproducible process conditions
Assemble, clean, sterilise, and disassemble fermentation vessels and related equipment
Prepare culture media, feeds, buffers, and probe calibration following established protocols
Handle microbial strains (primarily yeast initially, with mammalian cells introduced later) under sterile conditions
Data generation:
Generate reliable, high‑quality, well‑labelled datasets from probe measurements to train and validate InSpek’s AI and chemometric models
Maintain accurate, detailed experiment records with full sample traceability and consistent data logging
Format and organise results to support data analysis and model development, in coordination with the data/AI team
Use standard reference analytical techniques (e.g. Cedex) to provide reference values alongside the probe data
General lab support:
Draft technical reports, laboratory notebooks, and contribute to the documentation of procedures
Conduct routine maintenance and troubleshooting of fermentation systems and lab instruments
Manage lab operations, including cleaning, sterilisation, and inventory of consumables and media
Support lab organisation, always ensuring good hygiene and safety practices

COMPETENCIES / PROFIL

Bioprocessing track record: 2+ years of experience in running bioprocesses
Bioreactor operation: Ability to set up and operate bioreactors in batch and fed‑batch modes
Lab operations: Comfortable with routine lab operations, including media and buffer preparation, solution making, autoclave use, dishwashing equipment, and labware cleaning
Familiar with ordering lab supplies and maintaining inventory
Awareness of laboratory safety procedures and PPE requirements
Startup mindset: Proactive, eager to learn, and comfortable working in a fast‑paced environment
Languages: Fluency in English; French is a plus
Nice‑to‑have:
Experience with mammalian cell cultures
Familiarity with standard analytical techniques (e.g., HPLC, Cedex)
Previous exposure to Raman spectroscopy
Experience in regulated environments and knowledge of current Good Manufacturing Practices (cGMP)