Bioinformaticien – Ingénieur (F/H)

PSL Université Paris; Paris; Vor Ort; EUR 29.000 - 35.000; Vollzeit

Benefits dieser Stelle

Collective catering

70% transportation reimbursement

Supplementary health insurance

Zusammenfassung

The Curie Institute Research Center in Paris invites applications for a bioinformatician to join the Genomics and Development of Childhood Cancers lab. The role focuses on multi-omics analyses of fetal tissue and pediatric brain tumors using single-cell and spatial techniques.

Applicants should have a master/engineer degree in bioinformatics, solid computational skills, and experience with NGS/single-cell and spatial omics.

Qualifikationen

• Master or engineer degree in bioinformatics or related areas.
• Solid computational skills and strong interest in cancer biology, genomics and/or developmental biology.
• Experience with NGS/single-cell and spatial omics is required.

Aufgaben

• Conduct multi-omics characterization of human fetal tissue and childhood brain tumors using single-cell and spatial approaches.
• Collaborate with a multidisciplinary team in an international research environment.
• Contribute to data analysis and interpretation to advance the project goals.

Kenntnisse

NGS/single-cell genomics

Spatial omics

Computational skills

English proficiency

Ausbildung

Master or Engineer degree in bioinformatics or related areas

Jobbeschreibung

The Curie Institute Research Center

France’s leading cancer research and treatment centre, Institut Curie unites a renowned research centre and a specialist hospital, fostering close collaboration between scientists, clinicians and healthcare professionals. It offers an environment of excellence where expertise comes together around shared values: care, humanity, openness, collaboration, efficiency, innovation, solidarity and commitment.

Missions

Laboratories

The Genomics and Development of Childhood Cancers lab (https://institut-curie.org/team/saulnier), headed by Dr. Olivier Saulnier is looking for a motivated bioinformatician on cancer/single-cell genomics.

We are located in the heart of Paris at Institut Curie, one of the world’s leading institutions in cancer research. It represents an excellent and international environment with interdisciplinary expertise and high-quality technological platforms.

Missions

Our lab aims to better understand the development origins of childhood brain cancers. The project will involve multi-omics characterization of human fetal tissue and childhood brain tumors using single-cell and spatial approaches.

Key publications

1/ Saulnier*, Zagozewski*, Liang*, Hendrikse*, et al., A Group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing. Nature Cell Biology. 2024

2/ Visvanathan*, Saulnier*, Chuan*, et al., Early Rhombic Lip Protogenin+ve Stem Cells in a Human Specific Neurovascular Niche Initiate and Maintain Group 3 Medulloblastoma. Cell 2024

3/ Hendrikse*, Haldipur*, Saulnier*, et al., Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022

Training and experience required

• Training: Applicant should hold, or be in the process of completing, a master or engineer degree in bioinformatics or related areas
• Scientific skills: should have solid computational skills, and a strong interest in cancer biology, genomics and/or developmental biology
• Professional experience required: experience with NGS/single-cell, spatial omics

Skills required

• Language skills: very good English level and communication skills
• Ability to work independently, to communicate and to work in a team
• The candidate should be highly motivated, curious, and enthusiastic to work in a collaborative team

Contract information

Type of contract: Fixed-term contract

Starting date: As soon as possible

Duration: 2 years

Working time: full time

Remuneration: 31 750,59€ annual gross salary : according to the current grids

Benefits

• Collective catering
• reimbursement of transportation fees up to 70%
• supplementary health insurance

Location of the position

Paris

Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.

All our opportunities are open to people with disabilities