Assistant(e) ingénieur(e) (F/H) (F/H)

PSL Université Paris; France; Hybride; EUR 25 000 - 28 000; Plein temps

Avantages offerts par ce poste

Collective catering

Remboursement transport jusqu'à 70%

Assurance santé complémentaire

Résumé du poste

L’Institut Curie, centre de recherche et d’hôpital, recherche un Assistant Ingénieur en biologie à Orsay pour contribuer au développement de molécules thérapeutiques.

Diplôme Bac + 2 à Bac + 3 et 1–2 ans d’expérience en culture cellulaire; missions: culture cellulaire, tests de cytotoxicité, IP1, prolifération et invasion, extraction d’ARN et analyses RT-qPCR; poste en CDD d’un an, 39 heures/semaine, rémunération indiquée; avantages catering et remboursement transport.

Qualifications

• Formation Bac + 2 à Bac + 3 et expérience 1–2 ans en culture cellulaire.
• Connaissance de biologie cellulaire et moléculaire et tenue d’un carnet de laboratoire.
• Capacité à réaliser des tests de cytotoxicité et dosages IP1.

Responsabilités

• Assurer la culture de lignées cellulaires adhérentes.
• Réaliser des tests de cytotoxicité et des dosage IP1.
• Réaliser des essais de prolifération et d’invasion.
• Procéder à l’extraction d’ARN et analyses RT-qPCR.
• Collaborer avec chercheurs pour analyser les données expérimentales.

Connaissances

Biologie moléc

Analyse de résultats

Autonomie

Esprit d'équipe

Formation

Bac + 2 à Bac + 3 (BTS – Professional License - BUT)

Outils

Culture cellulaire

RT-qPCR

Extraction d’ARN

Description du poste

The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.

The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Missions

Activités principales

Laboratory
The 'Chemistry and Modelling for Cancer Biology' unit (UMR9187) is located at the Institut Curie research centre in Orsay. It is an interdisciplinary unit dedicated to designing and synthesising molecular probes and anti-cancer drug candidates and studying their mechanisms of action. The unit comprises 50 people and is supported by:

• three research teams.
• Two cross-disciplinary divisions (modelling and biology).
• the 'Chimiothèque' platform, which is one of the largest in France with almost 13,000 compounds resulting from 70 years of research.

https://institut-curie.org/unit/umr9187-u1196
https://institut-curie.org/team/verga

Missions

Our team is looking for a motivated Assistant Engineer (AE) in biology to contribute to a project involving the development of therapeutic molecules.

Description of the activities

• Ensure the culture of adherent cell lines (BS2)
• Perform cytotoxicity tests
• Perform IP1 (inositol monophosphate) dosage tests
• Perform proliferation and invasion tests
• Carry out RNA extraction and downstream analyses (RT-qPCR)
• Collaborate closely with researchers to analyze experimental data and contribute to the project's progress

Training and experience required

• Education: Bac + 2 to Bac + 3 (BTS – Professional License - BUT)
• Experience: At least 1 to 2 years of practical experience in cell culture

Knowledge

• Knowledge of cell and molecular biology
• Ability to analyze results obtained and write a laboratory notebook

Desired operational skills

• Apply hygiene and safety rules
• Master basic cell culture techniques in L2
• Maintain a high level of concentration during repetitive manipulations
• Demonstrate rigor in conducting experiments to ensure the quality and reliability of results
• Ensure the traceability of chemical compounds

Skills required

• English proficiency: B1 to B2
• Good organizational skills, ability to work autonomously and in a team
• Rigor, motivation, and enthusiasm for research

Contract information

• Type of contract: CDD
• Duration: 1 year
• Working time: full time - 39 hours per week
• Remuneration: from de 25131.77€ à 27504.77€ according to the current grids
• Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
• Location of the position: Orsay

All our opportunities are open to people with disabilities

Faithful to the legacy of its founder, the Institut Curie is deeply committed to promoting equal opportunities, diversity, and inclusion. Convinced that diversity of backgrounds and experiences contributes to collective performance, we strive to provide everyone with a respectful and equitable working environment and encourage all candidates to apply for our job opportunities.