Senior Scientist, Bivalent Modalities & PROTACs

Orion Corporation; Espoo; On-site; EUR 100,000 - 140,000; Full time

Benefits offered by this job

Health benefits

Relocation support

Job summary

Orion Corporation in Espoo, Finland, seeks an experienced Senior Scientist to drive medicinal chemistry strategies for bivalent induced proximity modalities such as PROTACs and RIPTACs. The role combines hands-on synthesis with design optimization across a diverse portfolio, advancing next generation modalities.

The position emphasizes building organizational capability in bivalent proximity approaches, with a focus on enabling long-term excellence.

Qualifications

• PhD in Chemistry or related field
• Strong background in organic synthesis, medicinal chemistry and lead optimization
• Experience with bivalent molecules, PROTACs, or related modalities

Responsibilities

• Design and synthesize novel bivalent induced proximity modalities (PROTACs, RIPTACs) including target binder development and linker optimization
• Build and expand diverse bRo5 chemical libraries aligned with project needs
• Perform multi-step organic synthesis, purification and characterization of new compounds
• Advance multi-parameter optimization addressing ADMET and developability challenges using computational tools

Job description

Orion Corporation in Espoo, Finland, seeks an experienced Senior Scientist to drive medicinal chemistry strategies for bivalent induced proximity modalities such as PROTACs and RIPTACs. The role combines hands-on synthesis with design optimization across a diverse portfolio, advancing next generation modalities.

The position emphasizes building organizational capability in bivalent proximity approaches, with a focus on enabling long-term excellence.