Scientist / Senior Scientist in Mass Spectrometry-based Proteome Research

Helsingin normaalilyseo - Helsinki Normal Lyceum; Helsinki; On-site; EUR 56,000 - 74,000; Full time

Benefits offered by this job

Health services and well-being support

Professional development opportunities

World-class research community

Job summary

The Viikki Proteomics Unit at the University of Helsinki is seeking a Scientist/Senior Scientist to deliver reliable proteomics services and support researchers. This hands-on role focuses on assay development, instrument operation, data analysis, and method standardization across HPC services.

Ideal candidates have 2+ years in proteomics, strong protein chemistry knowledge, and proficiency with MS data analysis tools.

Qualifications

• Master's degree in Chemistry, Biochemistry, Biology or a related life science.
• 2+ years of proteomics research experience.
• Strong background in protein chemistry.
• Experience in mass spectrometry-based proteomics is highly preferred.
• Proficiency with MS data analysis software.

Responsibilities

• Develop and optimize proteomics methods and workflows for core services.
• Operate day-to-day high-resolution LC-MS/MS instrumentation and sample prep.
• Support facility users with experimental design and data interpretation.
• Maintain records of instrument use, maintenance, and procedures.

Skills

MS data analysis

Detail-oriented

English proficiency

Collaboration

Education

Master's degree in Chemistry/Biochemistry/Biology or related life science

PhD preferred

Tools

Mass spectrometry software

Job description

About Us

The Helsinki Proteomics Center (HPC) is a state-of-the-art technology platform operating across two life-science campuses at the University of Helsinki. Dedicated to advancing proteomics research, we provide cutting-edge services and collaborate with researchers to explore protein functions, interactions, and dynamics. This position is based at the Viikki Proteomics Unit, which is part of the Helsinki Proteomics Center.

Your Role

We are seeking a highly motivated Scientist / Senior Scientist to join the Viikki Proteomics Unit. This is a primarily hands-on core-facility position: the appointee will help deliver reliable proteomics services, support facility users, maintain robust daily operations, and develop methods that can be implemented across the HPC service portfolio. The role is therefore best suited to a collaborative scientist who is motivated by enabling the research of others as well as advancing proteomics technology.

Key Responsibilities

Research and Development

• Investigate and evaluate new sample preparation protocols for bottom-up proteomics, including protein digestion, peptide clean-up, enrichment of post-translationally modified peptides, and handling sub-nanogram protein quantities.
• Optimize protocols for sensitivity, specificity, and reproducibility, and evaluate new MS data-acquisition and analysis workflows for implementation as new or improved HPC services.

Operational Support

• Perform day-to-day technical operation of the high-resolution LC-MS/MS systems.
• Prepare customer and internal samples using validated facility protocols.
• Participate in routine maintenance of existing equipment, quality-control checks, and troubleshooting.
• Maintain accurate records of instrument usage, downtime, maintenance, and experimental procedures.

Collaboration and Communication

• Work closely with HPC colleagues to maintain an efficient, safe, and well-organized core-facility laboratory, and coordinate priorities to deliver high-quality results within agreed timelines.
• Advise facility users on experimental design, sample requirements, available technologies, instrument capabilities and limitations, and realistic expected outcomes.
• Prepare clear reports, discuss results and appropriate next steps with users, and provide evidence-based recommendations to HPC leadership on new platforms, methods, and technologies.

Administrative Duties

• Oversee inventory and coordinate procurement to ensure uninterrupted operation of the Viikki Proteomics Unit.
• Work with service contract providers to restore operations of the LC-MS/MS system promptly after system downtime.

Qualifications

Educational Background

• Master's degree required; Ph.D. preferred in Chemistry, Biochemistry, Biology, or a related life science discipline.

Experience

• 2+ years of research experience with proteomic or related technologies.
• Strong background in protein chemistry is required.
• Experience in mass spectrometry-based proteomics is highly preferred.

Technical Skills

• Proficiency in using both vendor-specific and publicly available software tools for MS data analysis.
• Detail-oriented both at the lab bench and with record-keeping.
• Good command of English, both written and spoken.

Soft Skills

• Excellent time management and organizational abilities.
• Demonstrated ability to work effectively in a collaborative, service-oriented team environment.
• Willingness to learn, standardize, document, and routinely apply a range of sample preparation protocols.
• Ability to provide demonstrations and training to facility users with varying levels of proteomics experience.
• Motivation to expand data-analysis expertise and contribute to user support and reporting.

What We Offer

• The salary is based on the Finnish university salary system, depending on qualifications and experience.
• The University of Helsinki provides occupational health services, staff well-being resources, access to sports facilities, and extensive opportunities for professional development.
• You will join a world-class research community, work with cutting-edge technologies, and collaborate with leading experts in the field.

Join Us

Employment is expected to start on November-December, 2026, or as agreed. The position is initially offered for two years with the possibility of extension. A 6-month trial period will be applied. The formal title of the position will be determined according to the appointee's qualifications and experience: Research Coordinator/Postdoctoral Researcher / Specialist (for an appointee with a MSc).

The University of Helsinki welcomes applicants of any gender, age, linguistic or cultural background, or minority group.

About The University Of Helsinki

The University of Helsinki is Finland's leading multidisciplinary research university. Together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE), it forms an internationally recognized academic medical centre. HiLIFE was established in 2017 and supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.