Research technician in the Intracellular Compartmentation lab

Centre for Genomic Regulation; Barcelona; Presencial; EUR 30.000 - 50.000; Jornada completa

Descripción de la vacante

A leading biomedical research institute in Barcelona is seeking a Research Technician to join their Intracellular Compartmentation lab. This role involves collaborating with scientists on projects related to Golgi apparatus organization and secretion processes. Candidates should have a MSc in relevant fields and experience in molecular biology, including gene editing techniques. The position offers a stimulating environment with flexible working hours and a target start date as soon as possible.

Servicios

Flexible working hours

Extended vacation period

Professional career development opportunities

Formación

• Experience in cell biology and biochemistry.
• Proven experience with molecular biology and tissue culture work.
• Proficient in gene editing technologies.

Responsabilidades

• Work collaboratively in the lab on ongoing projects.
• Focus on Golgi apparatus organization and secretion processes.
• Develop procedures for testing TANGO1 function in skin fibrosis.

Conocimientos

Cell biology and biochemistry

Molecular biology

Tissue culture work

Microscopy imaging

Gene editing technologies (e.g. CRISPR-Cas9)

Cellular, molecular biology and microbiological skills

DNA & RNA techniques

Imaging skills (epifluorescence, confocal microscopy)

Protein analysis techniques

MS Office

Adobe Acrobat

ImageJ

Educación

MSc in biochemistry, biology, or biomedical sciences

Descripción del empleo

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Research technician in the Intracellular Compartmentation lab

The Institute

The Cent re for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

The Malhotra lab is looking to hire a research technician. The candidate will work together with scientists in the lab on ongoing projects, focussing mainly on Golgi apparatus organization and function, and the process of secretion of bulky cargoes such as collagens, mucins and chylomicrons. They will work with the Group Leader on a specific project related to the mechanism by which GRASP family of proteins function in unconventional secretion and with a postdoc, specifically, to develop procedures for testing the function of TANGO1 and its binding partner in skin fibrosis.

About the Lab

The Intracellular compartmentation lab studies different aspects of protein secretion. Protein secretion is an old problem of fundamental interest in cell biology. While over the last decades a lot of progress has been made in understanding protein secretion, a number of questions remain unsolved. The lab aims to understand different aspects of this. On the one hand they study the process whereby cytoplasmic, signal sequence lacking proteins are secreted from cells upon certain stimuli (known as unconventional protein secretion). On the other hand they focus on the transport and secretion of large, complex cargoes (like collagens and mucins) that do not fit the conventional secretory pathway.

Professional experience

Must Have

• You have experience in cell biology and biochemistry
• You have proven experience with molecular biology, tissue culture work, microscopy imaging
• You have proven experience in gene editing technologies (e.g. CRISPR-Cas9 editing of tissue culture cell lines)

Education and training

• You hold a MSc in disciplines such as biochemistry, biology, biomedical sciences

Languages

• You are proficient in English

Technical skills

• You have cellular, molecular biology and microbiological skills
• You have experience in gene editing techniques in tissue culture cells
• You have knowledge of DNA & RNA techniques
• You have imaging skills (epifluorescence as well as confocal microscopy, fixed cells as well as live cell imaging)
• You have experience in protein analysis techniques
• You have advanced software skills (MS Office, Adobe Acrobat, ImageJ)

Competences

• Excellent organizational skills
• Works well in a team, but is also capable of working in an independent manner

The Offer – Working Conditions

Contract duration: Technical and scientific activities contract linked to the project duration (estimated until 31/8/2027).

Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.

Target start date: As soon as possible.

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, race, religion or sexual orientation.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

• A motivation letter addressed to Dr Vivek Malhotra.
• Contact details of two referees.
• All applications must be addressed to Dr. Vivek Malhotra and be submitted online through the "Apply" button below.

Selection Process

Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.

Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.

Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline

Please submit your application by November 7, 2025.

Suggestions

The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form.

https://recruitment.crg.eu/webforms/recruitment-contact-form-suggestionscomplaints