Director Drug Discovery Chemistry

LIM Global Consulting, S.L.; Madrid; Presencial; EUR 80.000 - 120.000; Jornada completa

Descripción de la vacante

A leading biotech consulting firm based in Spain is seeking a Director of Drug Discovery Chemistry to oversee the company's research and development in antimicrobial agents. The ideal candidate will have a Ph.D. in chemistry, with over 10 years of experience in drug discovery and a proven track record in developing therapeutic molecules. This role offers an opportunity to drive innovation and collaborate with a multidisciplinary team focused on global health improvements.

Formación

• 10+ years of industry experience in drug discovery.
• Expertise in modern methods in medicinal chemistry.
• Track record of advancing therapeutic molecules.

Responsabilidades

• Supervise day-to-day activities of the Research Chemistry group.
• Drive medicinal chemistry optimization for new therapeutics.
• Lead and mentor the Drug Discovery Chemistry team.

Conocimientos

Medicinal chemistry SAR-driven optimization

Team leadership

Drug discovery experience

Collaboration skills

Educación

Ph.D. in synthetic organic chemistry or medicinal chemistry

Descripción del empleo

Our client is a solid technology company, now managing an emerging biotech platform dedicated to discovering and developing breakthrough antimicrobial agents to combat the growing threat of drug-resistant infections. Leveraging cutting-edge biology, advanced screening platforms, and a multidisciplinary team, they aim to deliver novel anti-infective therapies with transformative potential for global health.

Driven by a strong scientific and entrepreneurial spirit, the company is entering an exciting research & growth phase. We are now seeking a Director, Drug Discovery Chemistry, to lead and expand their Discovery Chemistry function, driving innovation, collaboration, and scientific excellence across their pipeline.

This position is based in Barcelona.

Main Responsibilities

• Directly supervise and manage the day-to-day activities of the Research Chemistry group, providing vision, inspiration, and both short-term and long-term goals. Communicate priorities, policies, and goals of Senior Leaders to the group.
• Perform medicinal chemistry SAR-driven optimization of novel small molecule and other drug modalities to provide overall optimal in vitro and in vivo properties of new anti-infective therapeutics.
• Champion and lead the Research chemistry efforts on multiple internal / external project teams, and demonstrate the ability to multi-task and parallel process to add to our continuous pipeline of development candidates.
• Identify new strategies and technologies and improve on existing platforms for pursuing novel synthesis of small molecule and other drug modalities.
• Set priorities, accelerate, and ensure successful progression of the group’s technology and pipeline projects.
• Actively participate in departmental, cross-functional, senior leadership, and external meetings to contribute expertise and to represent the goals and vision of the Discovery Chemistry group.
• Interact broadly and collaboratively with other groups, forging relationships and active collaborations.
• Challenge and mentor the Drug Discovery Chemistry group to provide opportunities, visibility, and development for all group members.
• Directly report to the General Manager.

Required Qualifications & Experience

• Have a Ph.D. in synthetic organic chemistry or in medicinal chemistry (Ph.D. in Chemistry or Pharmacy).
• Extensive drug discovery experience with small molecule and other drug modalities including their synthesis and manufacturing, and expertise in modern methods in medicinal chemistry structure-activity relationships.
• A minimum of 10 years of industry experience.
• Additional relevant experience should include an understanding of biological MOAs, extracellular / intracellular target evaluation, ADME / PK, PD / efficacy, tox evaluation.
• A track record of success in the field of novel therapeutic molecules, i.e., advancement of molecules into the clinic.
• Experience building leading teams is required.