Barcelona Director: Clinical & Quantitative Pharmacology

Alexion Pharma Spain S.L.; Barcelona; Híbrido; EUR 150.000 - 210.000; Jornada completa

Descripción de la vacante

AstraZeneca seeks a Director of Clinical Pharmacology and Quantitative Pharmacology in Barcelona. The role leads CP/QP strategy across development programs, guiding dose selection using population PK/PD, exposure−response, PBPK and QSP analyses.

You will influence pivotal decisions with cross‑functional partners and mentor a team of scientists. This senior leader drives regulatory strategy, contributes to IND/IBP/IMPD packages, shapes trial designs, and champions MIDD-driven decision making.

Formación

• Doctoral degree (PhD or equivalent) in clinical pharmacology, pharmacology, or related field.
• 10+ years post-doctoral experience in PK/PD and CP/QP components of early- and late-stage trials.
• Experience applying model-informed drug development (MIDD) strategies to inform program decisions.
• Knowledge of regulatory processes and experience contributing to IND/IMPD/IB submissions and pre-IND/IND meetings.
• Excellent written and verbal communication with multi-disciplinary leadership experience.

Responsabilidades

• Lead CPQP strategy and delivery across multiple programs.
• Develop and execute CP/QP plans and analyses (PK/PD, exposure-response, PBPK, QSP).
• Lead CP sections of early and late-stage protocols and development plans; recommend starting doses.
• Contribute to regulatory packages (IND, IB, IMPD) and study protocols/reports; articulate MIDD rationale.
• Provide integrated CP input across research, toxicology, immunogenicity, and regulatory teams.

Conocimientos

Clinical pharmacology

Model-informed drug development

Leadership

Communication

Strategic thinking

Educación

PhD in clinical pharmacology or related

Herramientas

NONMEM

Monolix

Phoenix

Simcyp

Descripción del empleo

AstraZeneca seeks a Director of Clinical Pharmacology and Quantitative Pharmacology in Barcelona. The role leads CP/QP strategy across development programs, guiding dose selection using population PK/PD, exposure−response, PBPK and QSP analyses.

You will influence pivotal decisions with cross‑functional partners and mentor a team of scientists. This senior leader drives regulatory strategy, contributes to IND/IBP/IMPD packages, shapes trial designs, and champions MIDD-driven decision making.