Senior Bioanalytical Assay Scientist

Zealand Pharma; Denmark; On-site; DKK 700,000 - 1,000,000; Full time

Job summary

Zealand Pharma A/S is seeking a Principal Technologist or Associate Scientist for Assay Development in the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. The role focuses on developing and qualifying high-quality assays to detect novel peptide therapeutics and to characterize immunogenicity during preclinical and clinical development.

You will support assay development, technology transfer to CROs, and generation of reagents, with hands-on lab work and thorough data

Qualifications

• Laboratory technologist qualification (e.g., biomedical laboratory technology) or a scientific degree (e.g., biology, biochemistry, pharmacy) with a clear interest in hands-on laboratory work
• 5 to 10 years of hands-on experience in development and qualification of assays including immunogenicity assays, biomarker assays, and quantitative ligand binding assays (cell-based and ligand binding formats)
• Good understanding of various analytical techniques used for biomolecules (e.g., ELISA, electrochemiluminescence, affinity chromatography, surface plasmon resonance, or related methods)
• Thorough understanding of analytical methods for quantifying, detecting, and characterizing drug-induced immunogenicity
• Excellent documentation and data analysis skills
• Proven ability to master core processes independently while being an effective team collaborator
• Proficient in English, both written and oral communication

Responsibilities

• Development and qualification of cell-based and ligand binding immunogenicity assays (anti-drug antibodies and neutralizing antibodies)
• Support general ligand binding assay development, qualification, and sample analysis as required
• Production, purification, and characterization of critical reagents
• Cell culture maintenance and optimization for assay purposes
• Support assay transfer and validation to contract research organizations (CROs)
• Data analysis, interpretation, and comprehensive documentation

Skills

Bioanalytical techniques

Assay development

Data analysis

Documentation

Team collaboration

English communication

Education

Biomedical laboratory technology

Biology/Biochemistry/Pharmacy

Tools

ELISA

Electrochemiluminescence

Affinity chromatography

SPR

Job description

Zealand Pharma A/S is seeking a Principal Technologist or Associate Scientist for Assay Development in the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. The role focuses on developing and qualifying high-quality assays to detect novel peptide therapeutics and to characterize immunogenicity during preclinical and clinical development.

You will support assay development, technology transfer to CROs, and generation of reagents, with hands-on lab work and thorough data