Senior Assay Development Scientist – Immunogenicity

Zealand Pharma A/S; Gladsaxe Kommune; On-site; DKK 700,000 - 1,100,000; Full time

Job summary

Zealand Pharma A/S is seeking a Laboratory-based Principal Technologist or Scientist to join the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. You will develop and qualify high-quality assays to detect novel peptide therapeutics and characterize immunogenicity during preclinical and clinical development.

You will support assay transfers to CROs, generate critical reagents, and contribute to data analysis and documentation in a collaborative, English-speaking

Qualifications

• Laboratory technologist qualification (e.g., biomedical laboratory technology) or a scientific degree (e.g., biology, biochemistry, pharmacy) with a clear interest in hands‑on laboratory work
• 5 to 10 years of hands‑on experience in development and qualification of assays including immunogenicity assays, biomarker assays, and quantitative ligand binding assays (cell‑based and ligand binding formats)
• Good understanding of various analytical techniques used for biomolecules (e.g., ELISA, electrochemiluminescence, affinity chromatography, surface plasmon resonance, or related methods)
• Thorough understanding of analytical methods for quantifying, detecting, and characterizing drug‑induced immunogenicity
• Excellent documentation and data analysis skills
• Proven ability to master core processes independently while being an effective team collaborator
• Proficient in English, both written and oral communication

Responsibilities

• Development and qualification of cell-based and ligand binding immunogenicity assays (anti-drug antibodies and neutralizing antibodies)
• Support general ligand binding assay development, qualification, and sample analysis as required
• Production, purification, and characterization of critical reagents
• Cell culture maintenance and optimization for assay purposes
• Support assay transfer and validation to contract research organizations (CROs)
• Data analysis, interpretation, and comprehensive documentation

Skills

Immunogenicity assays

Biomarker assays

Ligand binding assays

Cell-based assays

ELISA

Electrochemiluminescence

Surface plasmon resonance

Data analysis

Education

Biomedical laboratory technology OR biology/biochemistry/pharmacy degree

Job description

Zealand Pharma A/S is seeking a Laboratory-based Principal Technologist or Scientist to join the Department of Pharmacokinetics, Immunogenicity & Bioanalytical Sciences. You will develop and qualify high-quality assays to detect novel peptide therapeutics and characterize immunogenicity during preclinical and clinical development.

You will support assay transfers to CROs, generate critical reagents, and contribute to data analysis and documentation in a collaborative, English-speaking