PhD: Enzyme Technology for Seaweed Polysaccharide Modifications

Danmarks Tekniske Universitet; Ørsted; On-site; DKK 357,000 - 469,000; Full time

Job summary

DTU Bioengineering seeks a highly qualified candidate for a 3-year PhD position in enzyme biotechnology focused on seaweed polysaccharide modifications. The project aims to develop sulfatases for enzyme-based modification reactions and robust S1 sulfatases, in collaboration with TUM and as part of the NEXTMARINE project.

The PhD is co-supervised by Prof. Volker Sieber (TUM) with potential research stays at TUM.

Qualifications

• Must have practical experience in detailed characterization of heterologous enzyme production.
• Experience with enzyme assays, preferably assay development.
• Understanding of reaction kinetics and enzyme protein characteristics.
• Link experimental work to enzyme function, robustness, and kinetics for practical applications.
• In silico work such as molecular docking and molecular dynamics will be done in a team.
• Strong interest in developing applied enzyme technology and collaborating across disciplines.

Responsibilities

• From enzyme discovery to function and kinetics assessment.
• Perform and interpret enzyme assays and kinetics analyses.
• Conduct in silico work (docking, dynamics) in a team setting.
• Supervise and teach BSc and MSc students where applicable.

Skills

Protein engineering

Molecular biology

Enzyme kinetics

Enzyme assays

Computational docking

Molecular dynamics

Research planning

Education

Two-year MSc or equivalent

Tools

Benchling

Protein design software

Molecular biology techniques

Enzyme purification

Molecular docking

Molecular dynamics

Job description

DTU Bioengineering seeks a highly qualified candidate for a 3-year PhD position in enzyme biotechnology focused on seaweed polysaccharide modifications. The project aims to develop sulfatases for enzyme-based modification reactions and robust S1 sulfatases, in collaboration with TUM and as part of the NEXTMARINE project.

The PhD is co-supervised by Prof. Volker Sieber (TUM) with potential research stays at TUM.