Scientist non-GMP PP Tech Area - all genders

Sanofi US; Frankfurt; Vor Ort; EUR 65.000 - 85.000; Vollzeit

Zusammenfassung

A leading biopharmaceutical company based in Frankfurt is seeking a Scientist to join their Tech area team. The role involves pioneering continuous production processes for microbial drug substances, supporting the scale-up and purification of products, and collaborating closely with development teams. Candidates should have a PhD in a relevant field or equivalent experience, along with strong teamwork and communication skills. This position offers opportunities for career growth and participation in exciting projects in the pharmaceutical sector.

Leistungen

High-quality healthcare

14-week paid family leave

Childcare benefits

Qualifikationen

• Advanced degree in biology, biotechnology, chemical engineering, or similar.
• Minimum 5 years experience in biologics production and purification.
• Experience with continuous production processes.

Aufgaben

• Support production and purification of drug substance materials.
• Evaluate and implement new technologies for production processes.
• Plan and execute experiments with in-process analytical methods.

Kenntnisse

Teamwork

Communication

Analytical Thinking

Project Management

Ausbildung

PhD in Natural Sciences or Engineering

Tools

MS Office

Data Analysis Programming

Jobbeschreibung

About the job:

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Our Team:

As Scientist in the Tech area within our non‑GMP Pilot Plant team, you'll be responsible for Pioneering in the establishment of continuous production processes for microbial end‑to‑end DS processes (USP and DSP), working at the interface between research, development, and production. Ready to get started?

The non‑GMP Pilot Plant Team of the Bioprocess Engineering Group is an integral part of the Microbial Platform within the global CMC development organization. Our core competency is the scale‑up of processes for the production of drug substance using microbial systems, including the development of innovative process solutions at pilot scale. We contribute to bringing innovative medicines to our patients by supplying materials for dossier‑relevant studies and providing crucial process data. In doing so, we combine various technical facilities and technologies in the areas of microbial fermentation and purification. So, if you are interested in advancing new technologies and shaping the future, become part of our growing team.

Main responsibilities:

• Support the production (USP) and Purification (DSP) of non‑GMP technical Drug substance material and process intermediates from the microbial project portfolio (e.g., Nanobody® molecules, Synthorin™ molecules, plasmids).
• Identification, evaluation, and implementation of new technologies at technical scale with focus on pioneering continuous and disposable production processes. This includes feasibility assessment of GMP facilities with regards to robustness, performance, and selection or design of new production facilities.
• Self‑reliant planning, scale‑up, supply and analysis of technical material and troubleshooting for microbial projects in non‑GMP technical scale.
• Characterization and evaluation of equipment and development of predictive models with regards to continuous processes and process scalability.
• Introduction of electronic systems and AI solutions for the digitalization of processes, workflows, documentation and analysis of process‑relevant production data.
• Support in the organization, coordination and optimization of lab and process procedures in accordance with local and global guidelines as well as safety regulations including the establishment of corresponding documents (protocols, safety evaluations, working procedures).
• Planning, execution, development and documentation of experiments including the related in‑process analytical methods.
• Securing the efficient and documented transfer of developed processes into GMP pilot plants and to other Sanofi sites including technical support and expertise.
• Responsible for assigned facility maintenance and adaptation to new projects.
• Close collaboration with development units, the Heads of non‑GMP PP (USP and DSP), GMP production, and active representative for non‑GMP Pilot Plant in project teams and cross‑functional initiatives.
• Studying specialized literature and attending scientific congresses and training courses to identify innovative processes and methods, as well as implementing the gained knowledge in the area of responsibility in coordination with the supervisor.

About You

Education and experience

• Advanced university degree (e.g. PhD or similar) in Natural Sciences or Engineering (Biology, Biotechnology, Chemical Engineering, or similar), or a minimum of 5 years of professional experience.
• Experience in the production (USP) and purification (DSP) of biologics with microbial systems.
• Experience with mammalian cell culture beneficial.
• Experience in the scale‑up and with continuous production processes.
• Experience in the identification, evaluation and implementation of new technologies.
• Experience in project management in international and interdisciplinary contexts.

Soft skills

• Strong teamwork and communication skills.
• Excellent organizational skills.
• Collaborative spirit for open exchange in cross‑functional teams.
• Independent work style and solution‑oriented approach.
• High self‑motivation, reliability, and sense of responsibility.
• Pioneering spirit and willingness to continuously learn.

Technical skills

• Knowledge and experience with production processes for biological products, particularly in the area of production and purification techniques for various modalities as proteins or plasmids.
• Process engineering understanding and knowledge in scale‑up of cultivation and purification processes.
• Knowledge of continuous production processes.
• Knowledge in bioanalytics.
• Knowledge in process digitalization.
• Programming skills and tools for data analysis and know‑how in multivariate data analysis beneficial.
• Analytical thinking and approach.
• Very good IT skills (MS Office) and knowledge in handling modern, IT‑supported plant systems.

Languages

• Excellent German and English skills, both written and spoken.

Why choose us?

• Bring the miracles of science to life alongside a supportive, future‑focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Benefit from a well‑thought‑out benefits package that rewards your contribution and commitment.
• We take care of you and your family with a wide range of health and social such as high‑quality healthcare, numerous prevention programs and coverage for long‑term illness. Our 14‑week paid family leave for both parents is outstanding as well as a wide range of childcare benefits.

EEO Statement

At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law.