Postdoctoral researcher in computational epigenetics

UNKNOWN; Erlangen; Hybrid; EUR 60.000 - 75.000; Vollzeit

Benefits dieser Stelle

30 days annual leave

Pension scheme

Annual bonus

Zusammenfassung

Friedrich-Alexander-Universität Erlangen-Nürnberg in Erlangen is inviting applications for a postdoctoral researcher to lead method development in computational epigenetics. The project aims to infer upstream regulators of DNA methylation from matched expression and methylation data using ML, network modeling, and standard bioinformatics pipelines.

We offer a competitive TV-L based salary with potential for an annual bonus, 30 days of leave, pension schemes, and flexible working hours.

Qualifikationen

• PhD completed or near completion with strong publication record.
• Ability to lead method development in computational epigenetics.
• Experience collaborating with wet lab scientists.

Aufgaben

• Lead method development for computational epigenetics project.
• Develop computational methods to infer upstream regulators of DNA methylation.
• Collaborate with wet lab scientists and publish results.

Kenntnisse

Computational biology

Machine learning

Reproducible research

Independent research

Publications track record

Ausbildung

PhD in bioinformatics / ML / CS

Master in CS / bioinformatics

Tools

Python

R

ML libraries

Jobbeschreibung

Department Artificial Intelligence in Biomedical Engineering

Biomedical Network Science Lab

https://bionets.tf.fau.de

• Regular promotion to the next level and increase in salary pursuant to the collective bargaining agreement for the public service of the German Länder (TV-L) or remuneration pursuant to the Bavarian Public Servants Remuneration Act (BayBesG) plus an additional annual bonus
• 30 days annual leave at five working days per week with additional free days on December 24 and 31
• Occupational pension scheme and asset accumulation savings scheme
• We are flexible regarding working hours and workplace.
• Although we are a computational lab, you can benefit from various ongoing collaborations with wet lab scientists.

Your Tasks

We are launching a high-risk high-gain project in the field of computational epigenetics: Our aim is to develop computational methods to infer upstream regulators of DNA methylation from matched gene expression and DNA methylation data, using a combination ML, network-based modeling, and classical bioinformatics pipelines. If such upstream regulators exist at all is currently unclear, but if they do, they would constitute a new functional class of proteins that not only regulate a fundamental biological program but are also putative targets for novel therapies in diseases driven by aberrant DNA methylation. We are seeking a creative and highly independent postdoctoral researcher to lead the method development in this project.

Your Profile

• Ability to independently carry out creative, rigorous, and reproducible scientific work in the field of computational biology/ML for omics, as evidenced through publications in leading life sciences and/or ML journals or conference proceedings.
• Strong interest in epigenetics and willingness to engage in collaborations with wet lab scientists.
• PhD (completed or almost completed) in bioinformatics, machine learning, computer science, or a related field.
• Master's degree in computer science, bioinformatics, applied mathematics, or a related field.

Additional Information

Please provide the following documents with your application:

• Cover letter where (i) you explain why you are interested in the position and (ii) briefly describe your two best publications and tell us why you are proud of them. Important: write this letter yourself, do not AI-generate it. Also provide links to your two best publications if they are available open-access.
• PDFs of your two best publications if they are not available open-access.
• CV including full list of publications and contact details for two referees.
• Transcripts and certificates for your Bachelor's degree, Master's degrees, and PhD degree (if already available).

Notice

For all job postings, the following applies: Friedrich-Alexander-Universität promotes equal professional opportunities for women. Women are therefore expressly encouraged to apply.

Severely disabled persons as defined by the German Severely Disabled Persons Act will be given preferential consideration if they have the same professional qualifications and personal aptitude and if the advertised position is suitable for severely disabled persons. Details can be found in the respective job posting under "Remarks".

At the applicant's request, the Equal Opportunities Officer may be included in the job interview without any disadvantage to the applicant.

All advertised positions are generally suitable for part-time work unless stated otherwise in the job posting.