PostDoc in Molecular and Oncological Gynecology - Klinik für Frauenheilkunde und Geburtshilfe

Universitätsklinikum Frankfurt; Dreieich; Vor Ort; EUR 60.000 - 80.000; Vollzeit

Zusammenfassung

A leading university hospital in Hessen is seeking a Postdoctoral Researcher in Molecular and Oncological Gynecology to investigate IVT-mRNA reactivation of tumor suppressor pathways in ovarian cancer. The role requires extensive experience with mouse models and offers benefits such as competitive salary, training, and childcare support.

Leistungen

Competitive salary based on collective agreement

Long-term security through company pension schemes

Health offerings: online and face-to-face courses

Free public transport ticket for all of Hessen

Part-time employment possible

Qualifikationen

• FELASA Certificate is mandatory.
• Valid proof of measles immunity / measles vaccination is required.
• Experience with mouse models, including tumor injection and i.v. treatments.

Aufgaben

• Conduct in-depth research into IVT-mRNA in ovarian cancer.
• Perform mouse model experiments including tumor induction.
• Develop patient-derived organoid cultures.

Kenntnisse

Experience with mouse models

Knowledge of oncological therapeutic approaches

FELASA Certificate

Jobbeschreibung

Postdoctoral Researcher – Molecular and Oncological Gynecology

The Department of Molecular and Oncological Gynecology at the University Hospital Frankfurt invites applications for a Postdoctoral Researcher position at earliest possible time to join an innovative project investigating IVT-mRNA-based reactivation of tumor suppressor pathways in ovarian cancer.

Responsibilities

• Conduct in-depth research into the role of IVT-mRNA in the restoration of tumor‑suppressor genes in ovarian cancer and reversing therapy resistance.
• Perform mouse model experiments, including tumor induction, in vivo drug treatment, and assessment of tumor response using bioluminescence imaging.
• Develop patient‑derived organoid cultures.
• Perform functional assays to assess cell viability, proliferation, apoptosis, and drug sensitivity in cancer models.
• Develop and implement innovative therapeutic strategies, including combination treatments with targeted IVT‑mRNA and cisplatin.
• Collaborate with a multidisciplinary team of researchers and clinicians to interpret experimental results and drive the research forward.

Qualifications

• FELASA Certificate is mandatory.
• Valid proof of measles immunity / measles vaccination is required.
• Experience with mouse models, including tumor injection, i.p. and i.v. treatments, and in vivo bioluminescence imaging.
• Knowledge of oncological therapeutic approaches, including combination therapies and targeted inhibition.
• Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.

Benefits and Other Information

• Competitive salary based on a collective agreement with an annual special payment.
• Long‑term security through company pension schemes.
• Internal and external training for professional development.
• Health offerings: regular online and face‑to‑face courses on nutrition, relaxation, sports, and exercise.
• Part‑time employment possible; childcare in our daycare centre and child care during holidays.
• Free public transport ticket for all of Hessen (Free State Ticket Hessen).
• Campus facilities: university campus, cafeteria, cafés.

Contact

Phone or Email: 069-6301-6894

We welcome applications from candidates of all genders. Women are especially encouraged to apply.