Postdoc (f/m/d) on Generative AI for de Novo Protein Design / Completed university studies (PhD) ...

Helmholtz Association of German Research Centres; Deutschland; Vor Ort; EUR 55.000 - 75.000; Vollzeit

Zusammenfassung

A leading research institution in Germany is seeking a Postdoc on Generative AI for de Novo Protein Design. The role involves designing AI models to create novel protein sequences and collaborating internationally. Candidates should have a PhD in a relevant field, strong programming skills in Python and C/C++, and experience with deep learning frameworks. The position offers excellent benefits, including a vibrant research community and support for work-life balance.

Leistungen

30 days of paid holiday leave

Company pension scheme

Employee discounts

Support for work-life balance

Qualifikationen

• Completed PhD in molecular biology, computational biology, bioinformatics, genetics, or equivalent.
• Solid foundation in structural biology and generative models.
• Previous experience or interest in protein design is a plus.
• Strong motivation for collaborative work.

Aufgaben

• Design generative AI models for protein sequences and structures.
• Engage with international collaborators.
• Supervise junior lab members.
• Present research results and publish findings.

Kenntnisse

Programming skills in Python

C/C++

CUDA

Experience with AlphaFold

Experience with deep learning frameworks

Ausbildung

PhD in a relevant field

Tools

TensorFlow

PyTorch

Slurm cluster environment

Jobbeschreibung

Area of research

Scientific / postdoctoral posts

Starting date

01.02.2026

Job description

Postdoc (f/m/d) on Generative AI for de Novo Protein Design

With cutting-edge research in the fields of ENERGY, HEALTH and MATTER, around 1,500 employees from more than 70 nations at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) are committed to mastering the great challenges facing society today.

The Center for Advanced Systems Understanding (CASUS) is a German-Polish research center for data-intensive digital systems research.

The Department of Machine Learning for Infection and Disease is looking for a Postdoc (f/m/d) on Generative AI for de Novo Protein Design.

Your tasks

• Design of generative AI models (e.g., VAEs, GANs, Diffusion Models) to create novel protein sequences, fold structures, and functional molecules
• Engage with our international collaborators (Berlin, Dresden, London, Zurich, Taipei etc.) to understand existing approaches and datasets of natural and designed proteins
• Collaborate in the research team on other questions of machine learning, functional genomics, and genome instability
• Supervise junior lab members
• Present results at scientific meetings and publish high-impact peer‑reviewed research

Your profile

• Completed university studies (PhD) in a relevant field, such as molecular biology, computational biology, bioinformatics, genetics, computer science, mathematics, or equivalent scientific background
• A solid background and motivation to learn more about structural/molecular biology, protein biophysics, generative models, software engineering, or a related subject
• Previous experience or interest in Generative Modelling, Protein Folding/Design, and Structural Biology is a plus
• Experience with AlphaFold, RFdiffusion, and RFdiffusion2 is a significant plus
• Strong motivation to work in a collaborative multidisciplinary environment
• Excellent programming skills in languages such as Python, C/C++ and CUDA
• Familiarity with modern deep learning frameworks like Tensorflow 2.x.x, PyTorch
• Mandatory experience with High-Performance Computing (HPC) cluster environments and the Slurm cluster environment is required
• Communication skills in English and in a professional context (presentation of research results at scientific meetings, colloquial discussions, writing of manuscripts)

Our offer

• A vibrant research community in an open, diverse and international work environment
• Scientific excellence and extensive professional networking opportunities
• Salary and social benefits in accordance with the collective agreement for the public sector (TVöD-Bund) including 30 days of paid holiday leave, company pension scheme (VBL)
• We support a good work‑life balance with the possibility of part-time employment, mobile working and flexible working hours
• Numerous company health management offerings
• Employee discounts with well‑known providers via the platform Corporate Benefits
• An employer subsidy for the "Deutschland‑Ticket Jobticket"

We look forward to receiving your application documents (including cover letter, CV, diplomas/transcripts, etc.), which you can submit via our online‑application‑system.

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.