PhD position in cortical synaptic connectivity in mouse & human (multi-neuron patch-clamp)

Charité-Universitätsmedizin Berlin; Berlin; Vor Ort; EUR 35.000 - 50.000; Vollzeit

Zusammenfassung

A prominent medical research university in Berlin is seeking a motivated Ph.D. student to investigate synaptic connectivity in microcircuits. The research will involve high-throughput multi-neuron patch-clamp techniques in both mouse and human brain slices. Ideal candidates should possess an MSc. in Neuroscience or related fields, with skills in neurophysiology and data analysis. Opportunities for training and international collaborations will be provided, along with a stimulating research environment.

Leistungen

Stimulating research environment

Training and professional development opportunities

International collaborations

Qualifikationen

• MSc. or equivalent in Neuroscience, Biology, or related field.
• Strong motivation for cellular and synaptic neurophysiology.
• Experience with immunohistochemistry or transcriptomics desired.
• Data analysis skills (Python and/or MATLAB) desired.

Aufgaben

• Investigate principles of local synaptic connectivity in cortical microcircuits.
• Map excitatory and inhibitory connectivity and network motifs.
• Utilize high-throughput multi-neuron patch-clamp techniques.

Kenntnisse

Cellular and synaptic neurophysiology

Immunohistochemistry

Transcriptomics

Data analysis (Python)

Data analysis (MATLAB)

Ausbildung

MSc. or equivalent in Neuroscience, Biology

Jobbeschreibung

PhD position in cortical synaptic connectivity in mouse & human (multi-neuron patch-clamp)

Position: Ph.D. Student

Deadline: 31 January 2026

City: Berlin

Country: Germany

Department: Institute of Cell and Neurobiology

Description:

Start: Fall 2026 (flexible)
Location: Berlin, Germany
Duration: 3 years (extension possible)
Salary: TV-L E13 (65%)

The newly establishing Emmy Noether junior research group of Yangfan Peng at the Institute of Cell and Neurobiology, Charité – Universitätsmedizin Berlin is recruiting a PhD student to investigate principles of local synaptic connectivity in cortical microcircuits using high-throughput multi-neuron patch-clamp (“multipatch”) in mouse and human acute brain slices. The project will focus on mapping excitatory and inhibitory connectivity and higher-order network motifs to understand microcircuit organization and its cross-species generalizability. See https://penglab.de/ and relevant publications below for further information.

We offer:

• A stimulating research environment with access to state-of-the-art methods
• Extensive training and professional development opportunities
• Opportunities for international and interdisciplinary collaborations
• A collaborative and supportive community with mentoring and supervision
• Access to human cortical brain tissue for slice experiments

Your profile

• MSc. or equivalent in Neuroscience, Biology, or related field
• Strong motivation for cellular and synaptic neurophysiology
• Experience with immunohistochemistry or transcriptomics desired
• Data analysis skills (Python and/or MATLAB) desired

Please send one PDF containing short motivation letter, CV, and contact information of 2 references to [e-mail]

PhD position in cortical synaptic connectivity in mouse & human (multi-neuron patch-clamp)
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