Bioinformatician / Computational Biologist (f/m/x)

Uniklinik Köln; Köln; Vor Ort; EUR 55.000 - 75.000; Vollzeit

Benefits dieser Stelle

Everything but ordinary

Work-life balance

Team spirit (R(h)ine culture)

Zusammenfassung

The University Hospital of Cologne is seeking a Bioinformatician/Computational Biologist to join the Department of Experimental Pediatric Oncology. You will analyze pediatric tumor genomics data, develop computational workflows, and integrate multi-omics data, with special emphasis on single-cell sequencing and spatial transcriptomics.

You will collaborate with experimental and clinical researchers, contributing to patient-centered cancer research within a leading university hospital setting.

Qualifikationen

• University degree in a relevant field (bioinformatics, computational biology, computer science, mathematics or physics).
• Advanced degree preferred (MSc/PhD); Bachelor with substantial research experience considered.
• Strong experience in analysis of high-throughput sequencing data, especially genomic and transcriptomic data.
• Solid programming skills in C++, R and/or Python; experience with large-scale biological data.

Aufgaben

• Analyze and interpret large-scale next-generation sequencing data from pediatric tumor samples.
• Develop and implement computational workflows and analysis pipelines.
• Integrate disparate molecular data types and visualize results.
• Emphasize single-cell sequencing and spatial transcriptomics to study tumor heterogeneity and microenvironment.
• Collaborate with experimental and clinical researchers and interact with Translational Genomics.

Kenntnisse

Genomics

Single-cell sequencing

Pediatric oncology

C++

Python

R

Data analysis

Communication

Ausbildung

Master's degree in bioinformatics

PhD in a related field

Tools

C++

R

Python

Spatial transcriptomics tools

NGS analysis pipelines

Jobbeschreibung

We are looking to support our rapidly growing team as soon as possible:

Bioinformatician / Computational Biologist (f/m/x)

Kinderklinik -Department of Experimental Pediatric Oncology

TV-L: 38,5 h/week (100%)

limited for 3 years according to WissZeitVGwithin the framework of a third-party funded project

Your salary will be based on TV-L

TV-L: 38,5 h/week (100%)

limited for 3 years according to WissZeitVGwithin the framework of a third-party funded project

Your salary will be based on TV-L

We are looking for a talented and motivated Bioinformatician/Computational Biologist/Computer Scientist with a strong interest in genomics and biology of pediatric cancer. The candidate will be involved in the analysis and interpretation of large-scale next-generation sequencing datasets from pediatric tumor samples. In addition, the candidate will contribute to the development and implementation of computational workflows and analysis pipelines for high-throughput genomic data and participate in the integration of different molecular data types. Particular emphasis will be placed on the analysis of single cell sequencing data and spatially resolved transcriptomics data to investigate tumor heterogeneity and tumor microenvironment interactions in neuroblastoma and related pediatric malignancies. Beyond computational analyses, the candidate will contribute to data interpretation, visualization, and the development of novel analytical concepts for the study of complex cancer genomic datasets. The position includes close collaboration with experimental and clinical researchers and will involve close interaction with the Department of Translational Genomics.

Your profile

The position requires a university degree in a relevant field, such as bioinformatics, computational biology, computer science, mathematics, physics, or a related discipline. Preferably, applicants hold an advanced degree (Master of Science or Ph.D.), although candidates with a Bachelor’s degree and substantial relevant research experience will also be considered. Applicants should have strong experience in the analysis of highthroughput sequencing data, particularly genomic and transcriptomic datasets. Solid programming and data analysis skills, preferably C++, R and/or Python, are expected, as well as experience working with large-scale biological data. A genuine interest in cancer biology and pediatric oncology research is essential. Experience with spatial transcriptomics or related spatial genomics technologies is highly desirable. Candidates should have good communication skills and be able to drive scientific projects with a high degree of independence.

Our offer

• Everything but ordinary: You can expect a secure job in a challenging, innovative environment – including company pension schemes and regular working hours without business trips.
• Work-life balance: Whether full-time or part-time, with or without children – with numerous support options, we will find the right path together.
• Team spirit in R(h)ine culture: You will be warmly welcomed by an interdisciplinary team that values mutual respect and helpfulness.
• Strong perspectives: We offer extensive training opportunities – so you can continuously grow and set new goals.

Your future with us

We are one of the leading university hospitals in Germany and network research, teaching and health care at the highest level. That's why many things are a lot bigger for us: the spectrum of exciting development opportunities. The limitless openness with which specialists from all over the world work together here. Or our commitment as an employer to support all employees as best we can in reconciling their job with their goals and life situations.

This is the University Hospital of Cologne: Everything but ordinary.

We are one of the leading university hospitals in Germany and combine cutting-edge research with clinical excellence. The Department of Experimental Pediatric Oncology provides a dynamic and highly collaborative research environment with strong connections between
basic science, genomics, and clinical oncology. The successful candidate will work in the group of PD Dr. Carolina Rosswog, embedded in the Department of Experimental Pediatric Oncology led by Prof. Matthias Fischer. The candidate will collaborate closely with Bioinformaticians from the Department of Experimental
Pediatric Oncology and from the group of Prof. Martin Peifer from the Department of Translational Genomics. The University Hospital Cologne provides access to state-of-the‑art genomics technologies, computational infrastructure, and interdisciplinary research networks.

People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification. The position is suitable for staffing with part‑time employees.

PD Dr. Carolina Rosswog

Tel: [phone]