Bioinformatician

German Cancer Research Center in the Helmholtz Association (DKFZ); Deutschland; Vor Ort; EUR 40.000 - 60.000; Vollzeit

Zusammenfassung

A leading cancer research center in Germany is seeking a highly motivated Bioinformatician to support cancer research projects. The role requires significant expertise in bioinformatics, particularly in NGS analysis and cancer genomics. The successful applicant will have the opportunity to drive their own research while collaborating with multidisciplinary teams. Competitive benefits include flexible working hours, excellent framework conditions, and 30 days of vacation per year.

Leistungen

30 days of vacation per year

Family-friendly working environment

Sustainable travel to work subsidy

Personal development opportunities

Corporate Health Management Program

Qualifikationen

• Significant expertise in bioinformatics or/and life sciences.
• Experience in NGS analysis.
• Ability to analyze multi-tier molecular profiling data.

Aufgaben

• Develop and support research projects in precision oncology.
• Analyze NGS and other high-throughput data.
• Drive development of new technologies for data analysis.

Kenntnisse

Bioinformatics expertise

Cancer genomics background

Bash scripting proficiency

R programming proficiency

Python knowledge

Git experience

Statistical analysis abilities

Excellent communication skills

Ausbildung

PhD in a relevant field

Tools

Cloud computing

NGS analysis tools

Jobbeschreibung

The German Cancer Research Center (DKFZ) is one of Europe’s largest cancer research centers. “Research for a life without cancer" is the mission of our world-class scientists and all our team members.

The DKFZ is a place where the brightest minds pursue bold ideas and seek answers to pioneering scientific questions through collaboration, innovation, and exploration across many disciplines. We provide a dynamic environment which empowers excellence with state-of-the‑art technologies, cutting edge infrastructure, and a global scientific network.

Contribute your knowledge, vision, and dedication to create a space where scientific discovery in cancer research is transformed into benefits for human health.

The National Center for Tumor Diseases (NCT) is a long-term cooperation between the German Cancer Research Center, excellent partners in university medicine and other research institutions at six locations in Germany. The goal of the NCT is to bring promising results from cancer research into clinical application quickly and safely. This approach is intended to provide cancer patients with nationwide access to innovative treatment options.

One of the six NCT sites is the NCT Dresden (NCT/UCC), which is a collaboration between the DKFZ, the University Hospital Carl Gustav Carus Dresden (UCC), the Carl Gustav Carus Medical Faculty of the TU Dresden and the Helmholtz Center Dresden-Rossendorf (HZDR).

For the Department ofTranslational Medical Oncologyat theNCT site Dresden, we are seeking for the next possible date a

Bioinformatician

Reference number: 2025-0297

NCT and DKFZ have laid the groundwork to address new challenges in personalized oncology through the MASTER program. This prospective registry trial employs very comprehensive molecular profiling and integrated data analysis (WGS/WES, RNA sequencing, genome-wide DNA methylation profiling; whenever possible, mass spectrometry-based (phosphor)proteomics, ex vivo drug sensitivity profiling, and spatial resolution of the immune environment). Based on the MASTER workflow, we provide clinically relevant management recommendations in a multicenter molecular tumor board (MTB) and follow up on clinical management of patients. The resulting multidimensional clinical and molecular dataset has kick‑started very successful interdisciplinary research projects (e.g., Heining et al. Cancer Discov 2018, Gröschel et al. Nat Commun 2019, Horak et al. Cancer Discov 2021, Möhrmann et al. Nat Commun 2022, Jahn et al. Ann Oncol 2022).

Your Tasks

The Department of Translational Medical Oncology investigates the molecular and cellular mechanisms for cancer development, proliferation, and evolution. To strengthen our expertise in bioinformatics and machine learning, we are offering a position for a highly motivated scientist with significant experience in bioinformatics, ideally in the field of cancer research. You will be given the opportunity to develop your own research profile and standing in precision oncology and are expected to support the department’s research projects as well as write your own grant applications. The position is integrated in a multidisciplinary team of clinicians, scientists, and bioinformaticians and offers access to the MASTER dataset. As a successful applicant, you will drive your own research, analyze NGS and other high‑throughput data from patient cohorts and work on the development of improved NGS data analysis algorithms and design novel applications, e.g., for the integration of different data types.

Your Profile

• Significant expertise in bioinformatics or/and life sciences, with an excellent background in NGS analysis and relevant experience in the field, ideally with a PhD
• Background knowledge in cancer genomics
• Proficiency in Bash scripting and R and experience with cloud computing (required)
• Proficiency in Python and Git (preferred)
• Ability to perform bioinformatic and statistical analyses of multi‑tier molecular profiling data, including NGS and single‑cell NGS, and drive the development and implementation of new technologies
• High level of self‑motivation and the ability to develop and pursue research projects independently as well as in collaboration
• Excellent written and spoken English skills and strong communication skills

Applications should include a CV, cover letter, certificates, expected availability date, a complete list of publications and 2–3 references.

We Offer

• Excellent framework conditions: state‑of‑the‑art equipment and opportunities for international networking at the highest level
• 30 days of vacation per year
• Flexible working hours
• Remuneration according to TV‑L incl. company pension scheme and capital‑forming benefits
• Possibility of mobile work and part‑time work
• Family‑friendly working environment
• Sustainable travel to work: subsidized Germany job ticket
• Unleash your full potential: targeted offers for your personal development promote your talents
• Our Corporate Health Management Program offers a holistic approach to your well‑being

Contact

JuliaDorok
Phone: [phone]

The position is initially limited to 2 years, with the possibility of prolongation.

Application Deadline

16.12.2025

Applications by e‑mail cannot be accepted.
Please also note that we cannot return applications submitted by post.

Are you interested?

Then become part of the DKFZ and join us in contributing to a life without cancer!

Notice

We are subject to the regulations of the Infection Protection Act (IfSG). Therefore, all our employees must provide proof of immunity against measles.

We are convinced that an innovative research and working environment thrives on the diversity of its employees. Therefore, we welcome applications from talented people, regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical ability, religion and age. People with severe disabilities are given preference if they have the same aptitude.

Share this job!

Deutsches Krebsforschungszentrum | Im Neuenheimer Feld 280 | 69120 Heidelberg | www.dkfz.de