Technical R&D - Analytical Project Lead

ITech Consult AG; Basel; On-site; CHF 140,000 - 190,000; Full time

Benefits offered by this job

100% Pensum

Job summary

ITech Consult AG in Basel seeks a Technical R&D - Analytical Project Lead to drive the development of analytical control packages for synthetic molecules, focusing on peptides and APIs. You will mentor junior scientists, coordinate external testing at CDMOs/CLOs, and ensure data integrity across regulatory dossiers.

The ideal candidate holds a Master’s or PhD in chemistry or pharmacy, with 5+ years in analytical development, and fluent English; German is a plus.

Qualifications

• Advanced degree in chemistry or pharmacy.
• 5 years of experience in analytical development of synthetic peptides.
• Robust LC experience (HPLC/UHPLC) with MS/UV/Fluorescence/CAD.
• Solid understanding of GC, titrations, and physicochemical methods.
• Strong collaboration, supervision and project management skills.
• Digital acumen and statistical analysis of analytical data advantageous.
• Excellent command of English.

Responsibilities

• Lead development of state-of-the-art analytical control packages for synthetic molecules, intermediates, and crude APIs.
• Contribute to portfolio delivery by optimizing process analytics using modern techniques.
• Coach technicians and junior scientists and act as central project contact.
• Supervise internal lab activities and testing at CDMs/CLOs.
• Collaborate cross-functionally with Research, Regulatory and Quality.
• Author/review regulatory dossiers ensuring data integrity.
• Lead external testing activities at CDMOs/CLOs as CPL.

Skills

HPLC/UHPLC

MS (Mass Spectrometry)

UV detection

Fluorescence detection

CAD (Charged Aerosol Detection)

Statistical data analysis

Project management

Coaching/mentoring

Education

Master's or Ph.D. in chemistry or pharmacy

Job description

Technical R&D - Analytical Project Lead: Analytical development / Synthetic Peptides / UV / Mass Spectrometry (MS) / Fluorescence / HPLC, GC English / Deutsch

Background:

Pharma Technical Development (PTD) is a global team of over 2,000 experts focused on developing innovative medicines to address patients' needs.

Within PTD, Synthetic Molecules Technical Development (PTDC) specializes in drug substance, drug product, and analytical sciences. PTDC is instrumental in advancing the synthetic molecules pipeline, supporting research, early development, and clinical trials through technical innovation and collaboration.

This opportunity lies within analytical development for synthetic molecules, where cutting-edge techniques like high-performance liquid chromatography, gas/ion chromatography, and mass spectrometry are employed to develop efficient and robust analytical methods. The goal is to ensure the release of clinical trial products and their eventual commercial supply through a strong control strategy.

The Perfect Candidate

holds an advanced degree in chemistry or pharmacy and brings a minimum of five years of professional experience in the analytical development of synthetic drug substances with a specialization for peptides. You are a technical expert in liquid chromatography (including HPLC, UHPLC, and advanced detection methods like MS) who can independently drive the development of analytical control packages for intermediates and APIs. As a natural leader and communicator with an excellent command of English, you excel at coaching junior staff, managing external CDMO/CLO activities, and collaborating cross-functionally to deliver seamless project execution. Finally, you possess strong digital acumen, a rigorous approach to statistical data, project management experience, and proven experience authoring critical regulatory dossiers (such as INDs and NDAs) to ensure total data integrity.

Tasks & Responsibilities:

• You serve as the Analytical SME/analytical project lead (APL), driving the development of state-of-the-art analytical control packages for synthetic molecules, including direct materials, IPCs, intermediates, and crude APIs.
• You actively contribute to portfolio delivery by ensuring efficient and effective process development analytics, including the adoption of modern techniques like modeling and simulation.
• You coach technicians and junior scientists on project work and serving as a central point of contact for project-related information
• You supervise internal laboratory activities and / or testing activities at CLOs/CDMOs
• You collaborate cross-functionally with key partners in research and early development, Regulatory, and Quality to ensure seamless project execution and alignment.
• You author, review, and approve critical documents and regulatory dossiers (e.g., QIMPD, NDA) while ensuring compliance with quality standards and data integrity.
• You act as a Chemistry Project Lead (CPL), leading external testing activities at CDMOs or CLOs.

Must Haves:

• A Master's or Ph.D. in chemistry, pharmacy, or a related field
• 5 years of professional experience within the analytical development of synthetic peptides
• You have a robust foundation in liquid chromatography (HPLC and UHPLC) with proficiency in various detection methods, including UV, Mass Spectrometry (MS), fluorescence, and charged aerosol detection
• You possess a solid understanding of analytical chemistry, particularly chromatographic techniques (HPLC, GC), titrations, and various physicochemical methods
• You demonstrate excellent collaboration, technical supervision, and project management skills, with a structured and rigorous approach
• Digital acumen to support digital transformation initiatives; familiarity with statistical analysis of analytical data is also advantageous
• You hold excellent command of the English language

Nice to Haves:

• Proficiency in German

Reference Nr.: 925401
Rolle: Technical R&D - Analytical Project Lead
Industrie: Pharma
Location: Basel
Pensum: 100%
Start: ASAP (01.03.2027)
Duration: 12++ Months
Deadline: 18/11/2026

About us:

ITech Consult is an ISO 9001:2015-certified Swiss company with offices in Germany and Ireland. ITech Consult specializes in placing highly qualified candidates for temporary staffing in the fields of IT, life sciences, and engineering. We offer temporary staffing and payroll services. This is free of charge for our candidates, and we do not charge any additional fees for payroll services.