Senior Scientist, Quantitative PK Modeling & Decision Support

CSL Plasma Inc.; Glattbrugg; Vor Ort; CHF 130.000 - 190.000; Vollzeit

Zusammenfassung

CSL Behring seeks a Senior Scientist in Quantitative Modeling & PK to advance non-clinical drug development using PK/PD, PBPK, QSP, and related modeling methods. You will design informative studies, analyze diverse data, and translate quantitative insights into actionable development decisions.

You will work closely with PK scientists and cross-functional teams to support regulatory submissions and project milestones in a fast-paced environment.

Qualifikationen

• Ph.D., M.Sc., or equivalent degree in Pharmacometrics, Pharmaceutical Sciences, Pharmacology, Biomedical Engineering, Applied Mathematics, Systems Biology, or a related discipline.
• Minimum 3 years of experience applying modeling and simulation approaches to support non-clinical drug development in a pharmaceutical, biotechnology, or CRO environment.
• Strong quantitative modeling skills with PK/PD, PBPK, QSP, and/or other mechanistic modeling approaches.
• Good understanding of PK, pharmacology, and non-clinical drug development including preclinical PK/PD studies.
• Experience using industry-standard modeling and data analysis tools such as Monolix, Simulx, NONMEM, R, MATLAB, Phoenix WinNonlin, or similar.
• Strong communication and collaboration skills in cross-functional teams.
• Scientific curiosity, integrity, sound judgment, and ability to work independently in a fast-paced environment.
• Experience with multiple drug modalities and/or therapeutic areas is desirable.

Aufgaben

• Apply fit-for-purpose quantitative modeling approaches to address non-clinical development questions, including candidate selection, study design, and FIH dose prediction.

Kenntnisse

PK/PD modeling

PBPK modeling

QSP modeling

NCA

Collaboration

Communication

Ausbildung

Ph.D./M.Sc. in Pharmacometrics or related field

Tools

Monolix

Simulx

NONMEM

R

MATLAB

Phoenix WinNonlin

Jobbeschreibung

CSL Behring seeks a Senior Scientist in Quantitative Modeling & PK to advance non-clinical drug development using PK/PD, PBPK, QSP, and related modeling methods. You will design informative studies, analyze diverse data, and translate quantitative insights into actionable development decisions.

You will work closely with PK scientists and cross-functional teams to support regulatory submissions and project milestones in a fast-paced environment.