Scientist Upstream

Incyte; Yverdon-les-Bains; On-site; CHF 120,000 - 180,000; Full time

Job summary

Incyte in Yverdon-les-Bains is seeking an Upstream Scientist for the Bioplant Process Sciences (BPS) department. The role provides upstream expertise for technology transfers, upstream process development, and implementing small-scale models for recombinant products.

The incumbent will lead upstream projects and share knowledge with BPS and Bioplant teams. The candidate will work in a highly regulated setting, coordinating with global teams to ensure robust data analysis, SOP drafting, and

Qualifications

• Master's degree in biotechnology or related field; PhD considered.
• At least five years of biotechnology experience, preferably in small-scale process development.
• Experience with cell culture bioreactors is required; protein purification/analytics is a plus.
• Ability to work in a highly regulated environment.
• Fluency in French and English.
• Strong team-oriented mindset.

Responsibilities

• Lead upstream studies and design BPS studies.
• Oversee technology transfers and small-scale model implementations.
• Lead Bioplant upstream investigations and experimental design of BPS studies.
• Support procurement of raw materials for new laboratory processes or studies.
• Lead data analysis and ensure data integrity of laboratory results.
• Serve as upstream SME during technology transfer meetings for new products.
• Participate in drafting SOPs and lab documents.
• Collaborate with on-site partner departments and US teams.

Skills

Cell culture

Upstream development

Bioreactors

Analytical methods

French & English (bilingual)

Education

Master's degree in biotechnology

PhD considered

Tools

Cell culture bioreactors

Protein purification

Analytics

Job description

Description

The Upstream Scientist in the Bioplant Process Sciences (BPS) department at Yverdon-les-Bains provides upstream expertise to both BPS and the Bioplant. This role supports technology transfers, upstream process development, and the implementation of small-scale models for new recombinant products. The Upstream Scientist also conducts BPS investigations and troubleshooting, leads upstream projects, and contributes expertise in small-scale cell culture bioreactors and related cell monitoring methods. In addition, the role supports raw material procurement for studies and is responsible for process implementation protocols, statistical analysis of results, and study reports within BPS. The Upstream Scientist shares technical knowledge with both BPS and Bioplant teams.

Aperçu

Description

The Upstream Scientist in the Bioplant Process Sciences (BPS) department at Yverdon-les-Bains provides upstream expertise to both BPS and the Bioplant. This role supports technology transfers, upstream process development, and the implementation of small-scale models for new recombinant products. The Upstream Scientist also conducts BPS investigations and troubleshooting, leads upstream projects, and contributes expertise in small-scale cell culture bioreactors and related cell monitoring methods. In addition, the role supports raw material procurement for studies and is responsible for process implementation protocols, statistical analysis of results, and study reports within BPS. The Upstream Scientist shares technical knowledge with both BPS and Bioplant teams.

Duties And Responsibilities

• Lead the preparation of cell culture study protocols and reports for small-scale implementation of new processes, facility-fit assessments, and other BPS studies. Support the preparation or review of similar purification protocols and reports.
• Lead the experimental design of BPS upstream studies and support purification study design as needed.
• Lead Bioplant upstream investigations and experimental design of BPS studies.
• Support procurement of raw materials needed to implement new laboratory processes or studies.
• Lead the experimental results analysis and ensure data integrity of BPS laboratory data.
• Is the upstream SME during technology transfer upstream meetings for new products at the Bioplant site.
• Contribute to BPS projects, including documentation, supplier coordination, and implementation of an electronic laboratory notebook system.
• Share cell culture and upstream equipment expertise with BPS laboratory colleagues.
• Contribute to drafting SOPs and other Bioplant Process Sciences laboratory documents.
• Participate in the qualification and commissioning of new laboratory equipment, including monitoring, URS, protocols, and reports.
• Support laboratory organization, external shipments, and ordering activities.
• Interact and collaborate with on-site partner departments as well as Process Sciences and Analytical Sciences teams in the United States.
• Promote a strong culture of integrity and business ethics.
• Act in compliance with legal and regulatory requirements, as well as company guidelines.

Requirement

• Master's degree from EPF or University in cell culture, biotechnology, or a related field, with demonstrated biotechnology experience. A PhD in Biotechnology will also be considered.
• Minimum of five years of biotechnology experience, preferably in a small-scale process development laboratory.
• Experience with cell culture bioreactors is required; experience in protein purification and/or analytics is an advantage.
• Ability to work effectively in a highly regulated environment.
• Fluency in French and English.
• Strong Team-Oriented Mindset.

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.