Postdoc

EPFL; Lausanne; On-site; CHF 90,000 - 120,000; Full time

Job summary

EPFL's Laboratory of Elisa Oricchio at ISREC seeks a highly motivated postdoctoral fellow in cancer biology, genetics, and epigenetics to advance tumor evolution research on the EPFL campus in Lausanne.

The role combines experimental work with potential for fellowships; prior experience with animal models, 3D culture systems, and computational analyses is advantageous. Salary follows EPFL standards and is commensurate with experience.

Qualifications

• PhD in cancer biology, genetics, or epigenetics.
• Proven research excellence and high-quality publications.
• Ability to work collaboratively in a multidisciplinary setting.

Responsibilities

• In the Oricchio lab, investigate molecular mechanisms driving tumor initiation and therapy responses.
• Characterize cancer-associated genomic alterations and their effects on chromatin/epigenome.
• Explore how remodeling chromatin 3D structure drives tumor development and immune interactions.

Skills

Publication record

Motivation & dedication

Team collaboration

Education

PhD in cancer biology/genetics/epigenetics

Tools

Animal models

3D culture systems

Computational analyses

Job description

Mission

We are seeking a highly motivated postdoctoral fellow with a strong background in cancer biology, genetics, and epigenetics. The ideal candidate will have a proven track record of scientific excellence, demonstrated through high-quality publications.

The position is available in the Laboratory of Elisa Oricchio at the Swiss Institute of Experimental Cancer Research ISREC at EPFL. The lab is part of the vibrant research community of the Swiss Cancer Center Leman and is located on the EPFL main campus.

Main Duties And Responsibilities

In the Oricchio lab, we investigate the molecular mechanisms that drive tumor initiation and determine responses to therapy. A comprehensive understanding of tumor evolution requires integrating both genetic and non-genetic mechanisms. Thus, our research begins with the functional characterization of cancer-associated genomic alterations to determine how they reshape the structure and function of the epigenome. Over the past years, we have shown that remodeling the chromatin 3D structure is a key driver of tumor development and progression and demonstrated how specific genomic alterations reprogram the crosstalk between cancer cells and immune cells.

We offer

The position provides an exciting opportunity to further develop and expand these lines of research, and candidates are also encouraged to apply for individual fellowships to strengthen their CVs and future career prospects. A strong motivation and exceptional level of dedication and work ethic are essential. Prior experience with animal models, 3D culture systems and/or computational analyses will be an advantage. The salary will be according to EPFL standards.

Contract Start Date : 01/01/2027
Activity Rate : 100.00
Contract Type: CDD
Duration: One year, renewable
Reference: 2405