Postdoc

École polytechnique fédérale de Lausanne, EPFL; Lausanne; On-site; CHF 70,000 - 95,000; Full time

Job summary

EPFL, the Swiss Federal Institute of Technology in Lausanne, invites applications for a Postdoctoral Fellow position in the Laboratory of Elisa Oricchio at ISREC. We seek a highly motivated researcher with strong background in cancer biology, genetics, and epigenetics.

The successful candidate will investigate molecular mechanisms driving tumor initiation and therapy responses, leveraging genomic and epigenomic approaches, and may apply for fellowships to advance their CV and career.

Qualifications

• PhD in cancer biology, genetics or epigenetics or related field.
• Strong publication record and documented research excellence.

Responsibilities

• Investigate molecular mechanisms driving tumor initiation and therapy responses.
• Characterize cancer genomic alterations and epigenome effects.
• Collaborate within a multidisciplinary EPFL ISREC team on cancer research.

Skills

Cancer biology

Genetics

Epigenetics

Education

PhD in cancer biology/genetics/epigenetics

Tools

Animal models

3D culture systems

Computational analyses

Job description

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EPFL, the Swiss Federal Institute of Technology in Lausanne, is one of the most dynamic university campuses in Europe and ranks among the top 20 universities worldwide. The EPFL employs more than 6,500 people supporting the three main missions of the institutions: education, research and innovation. The EPFL campus offers an exceptional working environment at the heart of a community of more than 18,500 people, including over 14,000 students and 4,000 researchers from more than 120 different countries.

Postdoc

Mission

We are seeking a highly motivated postdoctoral fellow with a strong background in cancer biology, genetics, and epigenetics. The ideal candidate will have a proven track record of scientific excellence, demonstrated through high-quality publications.

The position is available in the Laboratory of Elisa Oricchio at the Swiss Institute of Experimental Cancer Research ISREC at EPFL. The lab is part of the vibrant research community of the Swiss Cancer Center Leman and is located on the EPFL main campus.

Main duties and responsibilities

In the Oricchio lab, we investigate the molecular mechanisms that drive tumor initiation and determine responses to therapy. A comprehensive understanding of tumor evolution requires integrating both genetic and non-genetic mechanisms. Thus, our research begins with the functional characterization of cancer-associated genomic alterations to determine how they reshape the structure and function of the epigenome. Over the past years, we have shown that remodeling the chromatin 3D structure is a key driver of tumor development and progression and demonstrated how specific genomic alterations reprogram the crosstalk between cancer cells and immune cells.

We offer

The position provides an exciting opportunity to further develop and expand these lines of research, and candidates are also encouraged to apply for individual fellowships to strengthen their CVs and future career prospects. A strong motivation and exceptional level of dedication and work ethic are essential. Prior experience with animal models, 3D culture systems and/or computational analyses will be an advantage. The salary will be according to EPFL standards.

Informations