Internship LC-MS Bioanalytics (Basel, 6 months)

1201 F. Hoffmann-La Roche AG; Basel; On-site; CHF 20,000 - 31,000; Full time

Job summary

Roche is offering an internship in its Bioanalytics and Biomarkers lab within pRED in Basel, focusing on mass spectrometry and LC-MS/MS workflows. You will gain hands-on exposure to state-of-the-art bioanalytical technologies and contribute to method development across biological matrices.

As a master student in life sciences or analytical chemistry, you will work under supervision of a laboratory head and collaborate with a team of seven associates to deliver high-quality data for preclinical

Qualifications

• Ambitious master student enrolled in life sciences or analytical chemistry.
• Experience applying chromatographic-mass-spectrometric analytical methods.
• Systematic, precise, proactive team player with initiative.
• Proficient in English; German is a plus.

Responsibilities

• Gain hands-on exposure to bioanalytical technologies including uHPLC, triple quadrupole and high-resolution MS.
• Learn development and implementation of LC-MS/MS methodologies for quantitation of drugs in biological matrices.
• Apply analytical methods to biological study samples (preclinical and clinical) delivering high-quality data.
• Collaborate within a team of seven associates under supervision of a laboratory head.

Skills

Chromatography-MS methods

Analytical chemistry

Education

Master's student in life sciences / analytical chemistry

Job description

Position

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary, life-changing innovation at speed. At the intersection of science and innovation, pRED’s Pharmaceutical Sciences (PS) organisation enables the discovery and development of safe and effective therapeutics at optimal doses in relevant populations. By seamlessly integrating our three core pillars - Translational Safety, Translational Pharmacology, and Biomarkers, we drive end-to-end asset development across the entire value chain, from target assessment to on-market support. Within this framework, the Bioanalytics and Biomarkers (BioAM) department supports molecules of all therapeutic modalities and disease indications with innovative technological solutions. Aligning with our mission to continuously improve predictive accuracy and accelerate the development of tomorrow's therapeutics, we pioneer new ways of bioanalytical work to support the fast and successful filing of our compounds. We recognise that we constantly need to adapt and improve the way we work to be able to deliver what patients need next.

Opportunity

In this position, you will:

• Gain hands‑on exposure to state-of-the-art bioanalytical technologies, including ultra High Performance Liquid Chromatography (uHPLC), Triple Quadrupole and High Resolution mass spectrometers, and sample processors.
• Learn how to develop and implement innovative LC-MS/MS methodologies for the quantitation of drugs (e.g. small molecules, oligonucleotides, degraders, or large molecules) in biological matrices, increasing bioanalytical sensitivity to support pRED’s growing drug pipeline.
• Apply these analytical methods to biological study samples (preclinical and clinical), delivering high-quality data.
• Collaborate within a team of 7 associates under the supervision of a laboratory head and the guidance of experienced team members.

Who You Are

You are an ambitious master student who is currently enrolled in life sciences (preferably in the area of molecular life science or analytical chemistry) or in a gap year between degrees.

• Experienced in the practical application of chromatographic-mass-spectrometric analytical methods.
• A person who works systematically and precisely and brings a high level of initiative as well as a dedicated attitude.
• A proactive and transparent team worker.
• Proficient in English (German is a plus).

Additional information

The preferred start date of the internship is February 2027, with a duration of 6 months.

About Roche

Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future.

We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.

Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact. Let’s build a healthier future, together.