Internship LC-MS Bioanalytics

Biopharma Asia; Basel; Hybrid; CHF 20,000 - 27,000; Part time

Job summary

Roche is seeking a motivated master’s student in life sciences for a 6‑month internship in Bioanalytics and Biomarkers (BioAM) at pRED in Basel. You will gain hands‑on experience with state‑of‑the‑art LC‑MS/MS technologies and contribute to the development of analytical methods for drug quantitation in biological matrices.

You will work in a small team under a laboratory head, applying LC‑MS/MS workflows to biological samples and supporting data generation for preclinical and clinical studies.

Qualifications

• Master's student enrolled in life sciences or a related field.
• Experience applying chromatographic–MS methods in a lab setting.
• Precise, systematic approach with initiative.
• Team-oriented with good English communication (German a plus).

Responsibilities

• Gain hands-on exposure to uHPLC, triple quadrupole, and high‑resolution MS.
• Develop and implement LC‑MS/MS methods for quantitation in biological matrices.
• Apply analytical workflows to preclinical and clinical samples to generate high-quality data.
• Collaborate within a 7-person BioAM team under supervision of a lab head.

Skills

Chromatographic–mass spectrometric

Systematic and precise work

Initiative and proactivity

Team collaboration

English proficiency

Education

Master's student in Life Sciences or analytical chemistry

Tools

uHPLC / LC-MS/MS instrumentation

Bioanalytical sample prep

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary, life-changing innovation at speed.

At the intersection of science and innovation, pRED’s Pharmaceutical Sciences (PS) organisation enables the discovery and development of safe and effective therapeutics at optimal doses in relevant populations. By seamlessly integrating our three core pillars, Translational Safety, Translational Pharmacology, and Biomarkers, we drive end-to-end asset development across the entire value chain, from target assessment to on-market support.

Within this framework, the Bioanalytics and Biomarkers (BioAM) department supports molecules of all therapeutic modalities and disease indications with innovative technological solutions. Aligning with our mission to continuously improve predictive accuracy and accelerate the development of tomorrow's therapeutics, we pioneer new ways of bioanalytical work to support the fast and successful filing of our compounds. We recognise that we constantly need to adapt and improve the way we work to be able to deliver “what patients need next.”

The Opportunity

In this position, you will:

Gain hands-on exposure to state-of-the-art bioanalytical technologies, including ultra High Performance Liquid Chromatography (uHPLC), Triple Quadrupole and High Resolution mass spectrometers, and sample processors.

Learn how to develop and implement innovative LC-MS/MS methodologies for the quantitation of drugs (e.g. small molecules, oligonucleotides, degraders, or large molecules) in biological matrices, increasing bioanalytical sensitivity to support pRED’s growing drug pipeline.

Apply these analytical methods to biological study samples (preclinical and clinical), delivering high-quality data.

Collaborate within a team of 7 associates under the supervision of a laboratory head and the guidance of experienced team members.

Who You Are

You are an ambitious master student who is currently enrolled in life sciences (preferably in the area of molecular life science or analytical chemistry) or in a gap year between degrees. Ideally, you bring the following skills and experience:

• Experienced in the practical application of chromatographic-mass spectrometric analytical methods.
• A person who works systematically and precisely and brings a high level of initiative as well as a dedicated attitude.
• A proactive and transparent team worker.
• Proficient in English (German is a plus).

Additional information

The preferred start date of the internship is February 2027, with a duration of 6 months.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.