Digital Biomarker Science & Technology Neuroscience Lead

Roche Holding AG; Basel; On-site; CHF 180,000 - 260,000; Full time

Job summary

Roche Holding AG sucht eine leitende Wissenschafts- und Produktrolle im Bereich Digital Biomarkers für Neurologie. Sie definieren die wissenschaftliche Vision, arbeiten eng mit Kunden und Partnern zusammen und führen interdisziplinäre Teams, um sensorbasierte Endpunkte zu entwickeln und zu validieren.

Sie beeinflussen die PRE-Sales-Kommunikation, führen Publikationen an und gestalten die regulatorische Strategie.

Qualifications

• Universitätsabschluss (Ph.D. oder gleichwertig) in Life Sciences; mind. 10 Jahre relevante Pharma-/Digital Health-Erfahrung.
• Nachweisliche Veröffentlichungen in hochrangigen Fachzeitschriften.
• Nachweis von Senior Stakeholder-Management und externen Kooperationen.
• Tiefe wissenschaftliche Produktmanagement-Erfahrung in großer Pharma-/Medtech-Firma.
• Erfahrung mit Sensor-Daten und digitalen Biomarkern.

Responsibilities

• Als wissenschaftlicher Product Owner übernehmen Sie die End-to-End-Entwicklung digitaler Biomarker-Lösungen.
• Führen Sie große interdisziplinäre Projektteams und definieren die wissenschaftliche Roadmap.
• Pflegen Sie Netzwerke mit Meinungsführern in Neurowissenschaften sowie Stakeholdern.
• Führen Sie Regulierungs-Strategien für digitale Endpunkte und deren Akzeptanz.
• Erklären Sie komplexe Daten in prägnante Lösungskonzepte in Pre-Sales.
• Veranstalten und präsentieren Sie wissenschaftliche Publikationen und Poster.

Skills

Sensor-Daten

Digital Biomarker

Stakeholder Management

Wissenschaftliches Produktmanagement

Leadership

Publikationskompetenz

Kommunikation

Klinische Neurologie

Education

PhD in Life Sciences

Job description

Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft. Werde Teil von Roche, wo jede Stimme zählt.

Die Position

Who we are:

We, the Digital Biomarker (dBM) and Remote Patient Management (RPM) Chapter in Roche Information Solutions, are an integrated team of scientists, technologists, data analysts and operations experts, that leverages mobile technologies like smartphones and wearables to bring the power of sensor measures to patients everywhere: in clinical drug trials and clinical care.

We drive research, workflows and analytics for Digital Biomarkers and Remote patient management in Roche Information Solutions. Together with our partners, we invent, design and deliver solution capabilities, products and services for better clinical research and improved healthcare outcomes. We co-create innovative digital remote monitoring concepts for sensitive and meaningful drug development endpoints, implement them in technology solutions, develop health related outcome measures with the data, seek community and regulatory acceptance of corresponding endpoints and offer them to Biopharma companies and research institutes for use in clinical trials. We are establishing the scientific foundations for disease monitoring and screening solutions in clinical practice and enable patients and healthcare providers to leverage the power of sensor data for better outcomes in the management of neurological disease, diabetes and others.

Here’s what we’re looking for:

Are you passionate about leveraging digital health technology (DHT) to revolutionize healthcare? At Roche, we are seeking a dedicated Digital Biomarker Science & Technology Neuroscience Lead to join our Digital Biomarker (dBM) and Remote Patient Management (RPM) Chapter. This pivotal role will drive the scientific product vision of our innovative digital biomarker solutions for Neurology. Based on a deep understanding of clinical trials in neurology in general and deep customer insights, you ensure that we meet the evolving needs of our BioPharma customers and their clinical trials.

You will shape the internal and external scientific communication of our products’ value propositions, actively engaging with prospective customers in a pre-sales capacity to translate complex scientific data into compelling solution strategies. Together with the scientific community, you will drive the acceptance of sensor-based outcome measures. acting as an influential scientific thought leader in the network of academia, industry, the patient community and regulators. Internally at Roche, you will lead cross-functional squads to develop and execute on the scientific product vision. As such, you will closely work with experts in the dBM & RPM chapter, cross-functional stakeholders across Roche Diagnostics and Pharma Global & Affiliate organizations.

Who You are:

• Collaborate with the International Product Manager for Chronic Remote Care Management to leverage scientific data insights and customer feedback to discover, develop and scale a product that is desirable, feasible and viable.
• Together with the International Product Manager for Chronic Remote Care Management, develop and cultivate networks with key opinion leaders for Neuroscience as well as with key stakeholders within the company.
• Partner with a broad stakeholder community of patients, care givers, physician and other experts to create scientific digital health solutions
• Act as scientific product owner for a set of digital biomarker solutions for Roche and external customers with needs in areas of Disease understanding / Drug portfolio decision-making (phase I-II) / Regulatory treatment approval (phase III-IV) / Clinical trial participant selection / Clinical care
• Oversee end-to-end scientific product research & development and the scientific roadmap
• Scientifically lead large interdisciplinary project teams that identify, design, develop and implement the scientific digital biomarker solutions to address the unmet measurement needs
• Drive the regulatory strategy for digital endpoint endorsement and qualification
• Drive scientific community acceptance of digital measures and maintain a strong network of collaborators spanning industry and academia
• Develop scientific core messages for product marketing
• Represent RIS scientifically in pre-sales conversations on Remote Patient Management and Digital Biomarker products
• Plan, initiate and co-author high-profile scientific publications and posters and represent Roche at relevant high-profile conferences
• Grow your influence as a respected scientific digital biomarker expert and advocate in the research and development community at Roche and externally through cross-industry task forces, communicating results at conferences and in peer-reviewed publications.
• Drive the scientific foundations of clinical use scenarios based on sensor-measurements to improve outcomes for patients as well as the efficiency of healthcare delivery

Who you are:

• University degree (Ph.D. or equivalent) in Life Sciences or related field with a minimum of 10 years related experience in the pharmaceutical and digital health industry
• Track record of writing compelling publications in high impact, peer-reviewed journals
• Proven experience with senior stakeholder management and external collaborations
• Deep scientific product management experience in a large Pharma or Medtech company
• Deep experience in the area of sensor data and digital biomarker development
• Provable experience leading in a matrix setup, recognized for embracing new ways of leading and working, with strengths in coaching and fostering a collaborative environment
• Transparent communicator and able to apply effective empowering leadership
• Previous clinical experience in chronic disease management and Neuroscience (especially Parkinson’s Disease, Huntington’s Disease, Multiple Sclerosis)

Should you have these additional nice-to-have skills, you are the ideal team member we are searching for:

• Comprehensive understanding of the current state of drug development for Parkinson's and Huntington's Disease
• In-depth knowledge of the clinical endpoint landscape and associated challenges in Parkinson's and Huntington's Disease
• Overview of existing digital biomarker approaches for these diseases
• Experience with developing digital outcome measures
• FDA/EMA regulatory interactions or regulatory consortias regarding clinical drug development and novel drug development endpoints

Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.

Wer wir sind

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.