Analytical R&D Project Lead – Synthetic Molecules (HPLC/MS)

Elan Personal AG; Basel; On-site; CHF 140,000 - 200,000; Full time

Benefits offered by this job

World-leading pharma group

Central Basel location

Further training opportunities

Dynamic, motivated team

Green campus and modern facilities

Job summary

Roche Switzerland invites applications for a Technical R&D - Analytical Project Lead in Basel. The role focuses on analytical development for synthetic molecules, including method development with HPLC/UHPLC and MS, and cross-functional project leadership across discovery, regulatory, and quality teams.

You will mentor staff, manage external testing at CDMOs/CLOs, and drive robust control strategies to ensure clinical release and supply readiness. English proficiency required, German a plus.

Qualifications

• Master's or PhD in chemistry, pharmacy or related field.
• Min. 5 years of professional experience in analytical development of synthetic peptides.
• Strong foundation in liquid chromatography (HPLC/UHPLC) with UV, MS, fluorescence and CAD detection.
• Solid understanding of analytical chemistry, chromatographic techniques (HPLC, GC) and related methods.
• Excellent collaboration, supervision and project management skills with a structured approach.
• Digital analytics familiarity to support data-driven transformations.
• Excellent command of English.

Responsibilities

• Drive development of analytical control packages for synthetic molecules, including materials, IPCs and crude APIs.
• Contribute to portfolio delivery with efficient process analytics and modern techniques.
• Coach technicians and junior scientists as project lead and POC for project information.
• Supervise internal labs and testing activities at external CDMOs/CLOs.
• Collaborate cross-functionally with Research, Regulatory and Quality for execution.
• Author, review and approve regulatory documents while ensuring data integrity.
• Act as Chemistry Project Lead, overseeing external testing activities at CDMOs/CLOs.

Skills

Analytical development

Project leadership

Team supervision

Cross-functional collaboration

Digital analytics

English proficiency

Education

Master's or Ph.D. in chemistry or pharmacy

Tools

HPLC/UHPLC

Mass spectrometry (MS)

UV detection

GC

Job description

Roche Switzerland invites applications for a Technical R&D - Analytical Project Lead in Basel. The role focuses on analytical development for synthetic molecules, including method development with HPLC/UHPLC and MS, and cross-functional project leadership across discovery, regulatory, and quality teams.

You will mentor staff, manage external testing at CDMOs/CLOs, and drive robust control strategies to ensure clinical release and supply readiness. English proficiency required, German a plus.