ADME/DMPK Technical Expert — PK/TK Insights & CRO Lead

Syngenta Group; Basel; On-site; GBP 70,000 - 110,000; Full time

Benefits offered by this job

Extensive benefits package including a

Pension scheme

Bonus scheme

Private medical & life insurance

Up to 31.5 days annual holiday

Large campus environment

Global team environment

Training options

Job summary

Syngenta Crop Protection seeks an experienced DMPK/ADME Technical Expert to join the Analytical Metabolism and Methods (AMM) group within Product Safety at Jealott’s Hill UK. You will design innovative ADME/PK/TK studies and interpret complex data to support crop protection product development and registration.

You will collaborate with metabolism teams, CROs, and regulatory bodies, ensuring timely data delivery and high-quality reports.

Qualifications

• Degree in biology or chemistry or equivalent.
• Significant knowledge in DMPK/ADME with PK/TK expertise.
• Familiarity with global regulatory guidelines (e.g. OECD 417) for GLP studies.
• Experience translating complex datasets into safety/regulatory insights.
• Practical PK/TK knowledge including non-compartmental analysis (NCA).
• Ability to collaborate with diverse scientific teams and external stakeholders.
• Organise and track complex scientific deliverables with attention to detail.
• Excellent oral and written communication for technical reports/presentations.
• Willingness to learn and apply new skills promptly.
• In-depth understanding of in vitro and in vivo xenobiotic metabolism desirable.
• Experience managing CRO-delivered services advantageous.

Responsibilities

• Overseeing CRO delivery and study strategy documents.
• Delivering technical insights from ADME and PK/TK data.
• Applying regulatory expertise to optimise study designs.
• Partnering with CROs to guide external study execution.
• Driving process improvements and reporting templates.
• Serving as a scientific contributor within the ADME/PK/TK area.

Skills

DMPK/ADME

PK/TK

Regulatory guidelines

Data interpretation

Cross-functional collaboration

Scientific communication

Project management

Learning mindset

Metabolism knowledge

Education

Biology or Chemistry degree

Job description

Syngenta Crop Protection seeks an experienced DMPK/ADME Technical Expert to join the Analytical Metabolism and Methods (AMM) group within Product Safety at Jealott’s Hill UK. You will design innovative ADME/PK/TK studies and interpret complex data to support crop protection product development and registration.

You will collaborate with metabolism teams, CROs, and regulatory bodies, ensuring timely data delivery and high-quality reports.