Senior Research Scientist - Bioanalysis

Charles River

Laval (administrative region)

On-site

CAD 85,000 - 112,000

Full time

4 days ago
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Benefits offered by this job

Free parking
Near Montmorency Subway
Electric vehicle charging station
Annual bonus
4 weeks vacation & 10 personal days
Health benefits

Job summary

Charles River is seeking a Method Development Research Scientist (Large Molecule) for the Bioanalysis team at the Laval location. You will act as a Study Director overseeing analytical studies using LC-MS/MS, HPLC-UV or other methods in GLP compliance, contributing to safety evaluation and drug development.

Responsibilities include developing workflows for proteins/peptides, executing experiments, interpreting data, and training staff.

Qualifications

  • Master degree in Chemistry, Biochemistry or related field with 2–3 years’ experience in a scientific position.
  • PhD degree in Chemistry, Biochemistry or related field.
  • Significant experience using LC-MS/MS and HPLC-UV with chromatographic data system.
  • Excellent time management, organizational, interpersonal and communication skills.

Responsibilities

  • Develop workflows and assays for analysis of proteins, peptides and PTMs across biological matrices.
  • Design and execute laboratory experiments including sample prep, mass spectrometry analysis and data interpretation.
  • Present complex datasets to internal teams, clients and stakeholders.
  • Train Associate Scientists and Analysts on sample prep and analytical techniques.
  • Prepare, review and maintain analytical procedures; provide recommendations to improve platform performance and data quality.
  • Evaluate and implement new technologies, tools and reagents to enhance capabilities and efficiency.

Skills

LC-MS/MS
HPLC-UV
Time management
Communication skills

Education

Master's degree in Chemistry/Biochemistry or related field
PhD in Chemistry/Biochemistry or related field

Tools

HPLC-UV

Job description

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For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Overview

As aMethod Development Research Scientist (Large Molecule) for our Bioanalysis team at the Laval location, you will act as a Study Director responsible for the conduct of all analytical and/or bioanalytical studies using LC-MS/MS, HPLC-UV or any other analytical detection method, in compliance with the Good Laboratory Practice (GLP) Regulations of the Organisation for Economic Co-operation and Development Principles and the US Food and Drug Administration (21 CFR Part 58 and subsequent amendments).

In this role, primary responsibilities include:

  • Developing workflows and assays for the analysis of proteins, peptides, and their post-translational modifications across a variety of biological matrices;
  • Designing and executing laboratory experiments, including sample preparation, mass spectrometry analysis, and data interpretation;
  • Presenting complex datasets in a clear and concise manner to internal teams, clients, and stakeholders;
  • Training Associate Scientists and Analysts on sample preparation procedures and analytical techniques;
  • Preparing, reviewing, and maintaining analytical procedures;
  • Providing scientific recommendations to improve platform performance and data quality;
  • Evaluating and implementing new technologies, tools, and reagents to enhance analytical capabilities and operational efficiency.

We are looking for the followingminimum qualifications for this role:

  • Master degree in Chemistry, Biochemistry or any other related field with at least 2 to 3 years’ experience in a Scientific position;
  • PhD degree in Chemistry, Biochemistry or any other related field;
  • Significant experience using LC-MS/MS and HPLC-UV with chromatographic data system;
  • Very efficient time management;
  • Excellent organizational, interpersonal and communication skills.

Role Specific Information:

  • Transportation: Free parking. Near the Montmorency Subway. Electric vehicle charging station;
  • Annual bonus based on performance;
  • Schedule: Monday to Friday daytime;
  • Permanent position as of the hiring, full-time 37.5hrs per week.

Why Charles River ?

  • We offer competitive benefits and advantages from day one to support your well-being;
  • Employee and family assistance program;
  • Excellent welcome program for new employees as well as in-house advancement and career development opportunities;
  • Access to a doctor and various health professionals (telemedicine);
  • 4 weeks’ Vacation & 10 Personal day policy;
  • Many social activities!

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.


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