Scientist

Frontage Laboratories; Vancouver; On-site; CAD 85,000 - 115,000; Full time

Job summary

Frontage Laboratories in Vancouver, Canada, is seeking an Associate Scientist with strong DMPK knowledge to join a fast-paced bioanalytical team. The role focuses on developing, validating and applying LC-MS/MS methods for small molecules and peptides across multiple matrices.

You will work with senior staff to ensure timely project delivery and regulatory compliance. The candidate should have a B.Sc or M.Sc in pharmaceutical sciences or chemistry, at least 3–5 years of relevant industry

Qualifications

• A minimum of 5 years’ experience for B.Sc (or 3 years for M.Sc) in pharma/biotech.
• Experience in HPLC and LC-MS/MS method development for small molecules, peptides, etc.
• Strong communication skills and ability to work in a fast-paced team.

Responsibilities

• Develop, optimize, and validate LC-MS/MS methods for small molecules and peptides.
• Perform quantitative bioanalysis of parent drug and metabolites.
• Analyze data with software (Sciex, MassLynx, GraphPad, LIMS).
• Operate and troubleshoot LC-MS/MS and HPLC platforms.
• Prepare study protocols and reports; coordinate with study teams.
• Ensure documentation and SOP compliance; support lab maintenance.

Skills

HPLC

LC-MS/MS

Bioanalysis

Communication skills

MS Excel

MassLynx

WinNonlin

GraphPad Prism

Education

B.Sc or M.Sc in pharmaceutical sciences, chemistry

Tools

Sciex Analyst

Sciex OS

MassLynx

GraphPad Prism

LIMS

MS Excel

MS Word

WinNonlin

Job description

Job Title : Scientist, BioA (Regular, full-time)

Frontage is a global Contract Research Company (CRO) with the head office located in Exton, Pennsylvania, USA . Frontage has 25 sites across USA, Canada, China and Italy. The Canadian operations include two sites – one located in Vancouver and the other based in Toronto. Frontage Vancouver (formerly BRI) has been in operation for more than 25 years with service offerings in regulated and non-regulated bioanalytical (various platforms including LC/MS/MS and MSD for small and large molecules analyses), In-vitro / In-vivo Drug Metabolism & Pharmacokinetics and pharmacology. The Frontage Vancouver operation is projected to grow significantly in the next few years, especially to meet the demands of biotech and pharmaceutical companies in the Pacific Northwest region. Our facility is accredited by AAALAC and conforms to GLP standards.

This Associate Scientist position requires teamwork and excellent oral and written communication skills with a strong understanding in DMPK and applied techniques.

Skills and Qualifications:

• Requires a B.Sc or M.Sc. in pharmaceutical sciences, chemistry (analytical and/or organic), or other science-related discipline.
• A minimum of 5 years’ experience for B.Sc (or 3 years for M.Sc) in pharmaceutical, biotech or similar industry.
• Experienced in HPLC and LC-MS/MS method development for small molecules, peptides, and other therapeutic modalities.
• Competent and self-motivated individual with the ability to work collaboratively and independently under moderate supervision in a fast-paced, matrixed team environment.
• Good verbal and written communication skills.
• Strong computers skills, and competent in using MS Word, MS Excel, Graphpad Prism, and WinNonlin.
• Good analytical, logical thinking and problem-solving skills, and the ability to adapt to changing priorities and deadlines.
• Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.

Job Responsibilities :

• Report to a senior team leader.
• Develop, optimize, and validate robust LC-MS/MS methods for small molecules, peptides, and other therapeutic modalities.
• Perform quantitative bioanalysis of parent drug and metabolites from various biological matrices.
• Perform data analysis and interpretation using different software programs (such as Sciex Analyst, Sciex OS, MassLynx, GraphPad prism, LIMS, MS Excel, etc.) and prepare study summaries.
• Operate, maintain, and troubleshoot LC-MS/MS and HPLC platforms.
• Prepare study protocols and study reports.
• Coordinate with study team members to execute studies and lead studies when required.
• Communicate and work closely with department leads to complete projects in a timely manner.
• Liaison /communicate results proficiently with study sponsors.
• Ensure that all applicable regulations, guidelines and BRI standard operating procedures are followed.
• Responsible and reliable record keeping, organization and assisting in lab management as needed.
• Ensure that all study related documentation is completed and archived as required.
• Contribute to basic lab maintenance such as equipment calibration, maintenance / cleaning, supply ordering, stocking, and follow-up.
• Follow safety policies and procedures.
• Other tasks as needed.
• Ability to lift 35 lbs, as needed.

Frontage is an Equal Opportunity Employer and provides equal opportunities to all employees.

We respect and seek to empower each individual and support the diverse cultures, perspectives, skills and experiences within our workforce. All employment is decided on the basis of qualifications, merit and business need.

We thank all applicants for their interest; however, only candidates under consideration will be contacted.